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- W2079675437 abstract "(+)-Frondosin A was isolated from the marine sponge Dysidea frondosa. The frondosins are interleukin-8 receptor antagonists -thus potent novel anti-inflammatory agents. They also exhibit some anti-HIV activity. Key points of the synthesis are: (1) the Charette asymmetric cyclopropanation by which A was transformed to C, (2) the Ru-catalyzed [5+2] cycloaddition (E→F) and (3) the ring expansion (H→I)." @default.
- W2079675437 created "2016-06-24" @default.
- W2079675437 date "2008-02-21" @default.
- W2079675437 modified "2023-10-18" @default.
- W2079675437 title "Synthesis of (+)-Frondosin A" @default.
- W2079675437 doi "https://doi.org/10.1055/s-2008-1042661" @default.
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