Matches in SemOpenAlex for { <https://semopenalex.org/work/W2079677140> ?p ?o ?g. }
- W2079677140 endingPage "559" @default.
- W2079677140 startingPage "550" @default.
- W2079677140 abstract "BackgroundCurrently, resection criteria for colorectal cancer liver metastases (CRCLM) are only limited by remnant liver function. Morbidity and survival after a partial hepatectomy with limited or extended indication criteria were compared.Methods/DesignBetween 1991 and 2010, patients undergoing a liver resection for CRCLM with limited (n = 169) or extended indication criteria (n = 129) were retrospectively identified in a prospectively collected single-centre database. Limited indication criteria were defined as less than three unilateral, not centrally located liver metastases in the absence of extra hepatic metastases. The extended criteria were only limited by predicted remnant liver volume and patients fitness. Data on co-morbidity, resection margin, short- and long-term morbidity, disease-free (DFS) and overall survival were compared.ResultsPatients with limited indications had less major complications (19.5% vs. 33.1%, P < 0.01), longer overall survival of 68.8 months [confidence interval (CI) 46.5–91.1] vs. 41.4 months (CI 33.4–49.0, P ≤ 0.001) and longer median DFS of 22.0 months [confidence interval (CI) 15.8–28.2] vs 10.2 months (CI 8.4–11.9, P < 0.001) compared with the extended indication group. Cure rates, defined as 10-year DFS, were 35.5% and 15.8%, respectively. Fewer patients in the extended indication group underwent an R0 resection (92.9% vs. 77.5%, P < 0.001). Only 17% of all R1 resected patients had recurrences at the transection plane.ConclusionA partial hepatectomy for CRCLM with extended indications seems justified but is associated with higher complication rates, earlier recurrence and lower overall survival compared with limited indications. However, the median 5-year survival was substantial and a cure was achieved in 15.8% of patients." @default.
- W2079677140 created "2016-06-24" @default.
- W2079677140 creator A5019509998 @default.
- W2079677140 creator A5023668532 @default.
- W2079677140 creator A5041852736 @default.
- W2079677140 creator A5041935065 @default.
- W2079677140 creator A5044305743 @default.
- W2079677140 creator A5057003857 @default.
- W2079677140 creator A5068862699 @default.
- W2079677140 creator A5074252488 @default.
- W2079677140 creator A5075342976 @default.
- W2079677140 creator A5085085591 @default.
- W2079677140 date "2014-06-01" @default.
- W2079677140 modified "2023-09-28" @default.
- W2079677140 title "Outcomes of extended versus limited indications for patients undergoing a liver resection for colorectal cancer liver metastases" @default.
- W2079677140 cites W1555541294 @default.
- W2079677140 cites W1881669090 @default.
- W2079677140 cites W1965164210 @default.
- W2079677140 cites W1969949460 @default.
- W2079677140 cites W1970844261 @default.
- W2079677140 cites W1977829624 @default.
- W2079677140 cites W1984013580 @default.
- W2079677140 cites W1987186772 @default.
- W2079677140 cites W1989175303 @default.
- W2079677140 cites W1989980011 @default.
- W2079677140 cites W1994770911 @default.
- W2079677140 cites W1997842170 @default.
- W2079677140 cites W2011890969 @default.
- W2079677140 cites W2014980719 @default.
- W2079677140 cites W2022595297 @default.
- W2079677140 cites W2027176779 @default.
- W2079677140 cites W2034782437 @default.
- W2079677140 cites W2045066689 @default.
- W2079677140 cites W2049399730 @default.
- W2079677140 cites W2058491683 @default.
- W2079677140 cites W2060959132 @default.
- W2079677140 cites W2076116834 @default.
- W2079677140 cites W2076480723 @default.
- W2079677140 cites W2081857912 @default.
- W2079677140 cites W2084470612 @default.
- W2079677140 cites W2085773264 @default.
- W2079677140 cites W2087157336 @default.
- W2079677140 cites W2092679286 @default.
- W2079677140 cites W2093524552 @default.
- W2079677140 cites W2096998881 @default.
- W2079677140 cites W2121425456 @default.
- W2079677140 cites W2125877119 @default.
- W2079677140 cites W2131266547 @default.
- W2079677140 cites W2143743735 @default.
- W2079677140 cites W2145070131 @default.
- W2079677140 cites W2148510223 @default.
- W2079677140 cites W2158918006 @default.
- W2079677140 cites W2161107000 @default.
- W2079677140 cites W2170281599 @default.
- W2079677140 cites W3191540504 @default.
- W2079677140 doi "https://doi.org/10.1111/hpb.12181" @default.
- W2079677140 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/4048077" @default.
- W2079677140 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/24246003" @default.
- W2079677140 hasPublicationYear "2014" @default.
- W2079677140 type Work @default.
- W2079677140 sameAs 2079677140 @default.
- W2079677140 citedByCount "43" @default.
- W2079677140 countsByYear W20796771402014 @default.
- W2079677140 countsByYear W20796771402015 @default.
- W2079677140 countsByYear W20796771402016 @default.
- W2079677140 countsByYear W20796771402017 @default.
- W2079677140 countsByYear W20796771402018 @default.
- W2079677140 countsByYear W20796771402019 @default.
- W2079677140 countsByYear W20796771402020 @default.
- W2079677140 countsByYear W20796771402021 @default.
- W2079677140 countsByYear W20796771402022 @default.
- W2079677140 countsByYear W20796771402023 @default.
- W2079677140 crossrefType "journal-article" @default.
- W2079677140 hasAuthorship W2079677140A5019509998 @default.
- W2079677140 hasAuthorship W2079677140A5023668532 @default.
- W2079677140 hasAuthorship W2079677140A5041852736 @default.
- W2079677140 hasAuthorship W2079677140A5041935065 @default.
- W2079677140 hasAuthorship W2079677140A5044305743 @default.
- W2079677140 hasAuthorship W2079677140A5057003857 @default.
- W2079677140 hasAuthorship W2079677140A5068862699 @default.
- W2079677140 hasAuthorship W2079677140A5074252488 @default.
- W2079677140 hasAuthorship W2079677140A5075342976 @default.
- W2079677140 hasAuthorship W2079677140A5085085591 @default.
- W2079677140 hasBestOaLocation W20796771401 @default.
- W2079677140 hasConcept C121608353 @default.
- W2079677140 hasConcept C126322002 @default.
- W2079677140 hasConcept C141071460 @default.
- W2079677140 hasConcept C159110652 @default.
- W2079677140 hasConcept C167135981 @default.
- W2079677140 hasConcept C2776909242 @default.
- W2079677140 hasConcept C2778132481 @default.
- W2079677140 hasConcept C2779013556 @default.
- W2079677140 hasConcept C3019894029 @default.
- W2079677140 hasConcept C44249647 @default.
- W2079677140 hasConcept C526805850 @default.
- W2079677140 hasConcept C71924100 @default.
- W2079677140 hasConcept C90924648 @default.
- W2079677140 hasConceptScore W2079677140C121608353 @default.