Matches in SemOpenAlex for { <https://semopenalex.org/work/W2079683527> ?p ?o ?g. }
- W2079683527 endingPage "658" @default.
- W2079683527 startingPage "651" @default.
- W2079683527 abstract "Homeobox containing genes are a family of transcription factors regulating normal development and controlling primary cellular processes (cell identity, cell division and differentiation) recently enriched by the discovery of their interaction with miRNAs and ncRNAs. Class I human homeobox genes (HOX genes) are characterized by a unique genomic network organization: four compact chromosomal loci where 39 sequence corresponding genes can be aligned with each other in 13 antero-posterior paralogous groups. The cardiovascular system is the first mesoderm organ-system to be generated during embryonic development; subsequently it generates the blood and lymphatic vascular systems. Cardiovascular remodelling is involved through homeobox gene regulation and deregulation in adult physiology (menstrual cycle and wound healing) and pathology (atherosclerosis, arterial restenosis, tumour angiogenesis and lymphangiogenesis). Understanding the role played by homeobox genes in endothelial and smooth muscle cell phenotype determination will be crucial in identifying the molecular processes involved in vascular cell differentiation, as well as to support future therapeutic strategies. We report here on the current knowledge of the role played by homeobox genes in normal and abnormal vasculogenesis and postulate a common molecular mechanism accounting for the involvement of homeobox genes in the regulation of the nuclear export of specific transcripts potentially capable of generating endothelial phenotype modification involved in new vessel formation." @default.
- W2079683527 created "2016-06-24" @default.
- W2079683527 creator A5018755607 @default.
- W2079683527 creator A5020467636 @default.
- W2079683527 creator A5023044832 @default.
- W2079683527 creator A5063136275 @default.
- W2079683527 date "2008-12-01" @default.
- W2079683527 modified "2023-10-18" @default.
- W2079683527 title "Homeobox genes in normal and abnormal vasculogenesis" @default.
- W2079683527 cites W1815472980 @default.
- W2079683527 cites W1964675052 @default.
- W2079683527 cites W1969067821 @default.
- W2079683527 cites W1970019361 @default.
- W2079683527 cites W1974303227 @default.
- W2079683527 cites W1985382182 @default.
- W2079683527 cites W1987713796 @default.
- W2079683527 cites W1988376520 @default.
- W2079683527 cites W1994638693 @default.
- W2079683527 cites W1997632855 @default.
- W2079683527 cites W1999776420 @default.
- W2079683527 cites W2000000541 @default.
- W2079683527 cites W2005245282 @default.
- W2079683527 cites W2005498969 @default.
- W2079683527 cites W2006574484 @default.
- W2079683527 cites W2007572774 @default.
- W2079683527 cites W2014077602 @default.
- W2079683527 cites W2017444273 @default.
- W2079683527 cites W2019590435 @default.
- W2079683527 cites W2033831066 @default.
- W2079683527 cites W2035543697 @default.
- W2079683527 cites W2039971642 @default.
- W2079683527 cites W2041056430 @default.
- W2079683527 cites W2041482422 @default.
- W2079683527 cites W2042720684 @default.
- W2079683527 cites W2043747135 @default.
- W2079683527 cites W2045960786 @default.
- W2079683527 cites W2049649964 @default.
- W2079683527 cites W2052487490 @default.
- W2079683527 cites W2053781137 @default.
- W2079683527 cites W2056611245 @default.
- W2079683527 cites W2056930699 @default.
- W2079683527 cites W2059215767 @default.
- W2079683527 cites W2061731694 @default.
- W2079683527 cites W2066171378 @default.
- W2079683527 cites W2068281991 @default.
- W2079683527 cites W2068494490 @default.
- W2079683527 cites W2070476377 @default.
- W2079683527 cites W2071061433 @default.
- W2079683527 cites W2072818545 @default.
- W2079683527 cites W2074140675 @default.
- W2079683527 cites W2075061052 @default.
- W2079683527 cites W2077135823 @default.
- W2079683527 cites W2077497255 @default.
- W2079683527 cites W2090817847 @default.
- W2079683527 cites W2092619818 @default.
- W2079683527 cites W2096166765 @default.
- W2079683527 cites W2097607520 @default.
- W2079683527 cites W2099959716 @default.
- W2079683527 cites W2100747051 @default.
- W2079683527 cites W2103588034 @default.
- W2079683527 cites W2105207670 @default.
- W2079683527 cites W2107326441 @default.
- W2079683527 cites W2107621463 @default.
- W2079683527 cites W2108394804 @default.
- W2079683527 cites W2115168535 @default.
- W2079683527 cites W2116115990 @default.
- W2079683527 cites W2116236561 @default.
- W2079683527 cites W2116512864 @default.
- W2079683527 cites W2133521971 @default.
- W2079683527 cites W2137570167 @default.
- W2079683527 cites W2140566949 @default.
- W2079683527 cites W2149374510 @default.
- W2079683527 cites W2153686053 @default.
- W2079683527 cites W2155206013 @default.
- W2079683527 cites W2162104331 @default.
- W2079683527 cites W2162614032 @default.
- W2079683527 cites W2168909179 @default.
- W2079683527 cites W2169284834 @default.
- W2079683527 cites W2169814977 @default.
- W2079683527 cites W2185961847 @default.
- W2079683527 doi "https://doi.org/10.1016/j.numecd.2008.08.001" @default.
- W2079683527 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/19013779" @default.
- W2079683527 hasPublicationYear "2008" @default.
- W2079683527 type Work @default.
- W2079683527 sameAs 2079683527 @default.
- W2079683527 citedByCount "44" @default.
- W2079683527 countsByYear W20796835272012 @default.
- W2079683527 countsByYear W20796835272013 @default.
- W2079683527 countsByYear W20796835272014 @default.
- W2079683527 countsByYear W20796835272015 @default.
- W2079683527 countsByYear W20796835272016 @default.
- W2079683527 countsByYear W20796835272017 @default.
- W2079683527 countsByYear W20796835272018 @default.
- W2079683527 countsByYear W20796835272019 @default.
- W2079683527 countsByYear W20796835272020 @default.
- W2079683527 countsByYear W20796835272021 @default.
- W2079683527 countsByYear W20796835272022 @default.
- W2079683527 countsByYear W20796835272023 @default.