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- W2079684416 abstract "Increased sensitivity to audiogenic seizures induced by reserpine was antagonized by dopa. The antagonism was dependent upon the conversion of dopa to dopamine in brain since blockade of both cerebral and extracerebral decarboxylase prevented the dopa effect, whereas blockade of extracerebral decarboxylase only did not affect the dopa antagonism. Increased seizure susceptibility occurred when brain levels of NE and DA were significantly lowered, while decreased susceptibility was found when brain levels of DA were significantly elevated. The results of this study indicate that dopamine plays a role in protection against audiogenic seizures in mice." @default.
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- W2079684416 title "Dopa reversal of reserpine enhancement of audiogenic seizure susceptibility in mice" @default.
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- W2079684416 doi "https://doi.org/10.1016/0031-9384(71)90028-x" @default.
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