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- W2079690248 abstract "Abstract This study investigated the effects of pravastatin and simvastatin in hypercholesterolemic patients with type 2 diabetes mellitus. Pravastatin and simvastatin were administered at the initial dosages approved in Japan (10 mg/d and 5 mg/d, respectively) to 40 patients using a crossover design. Pravastatin and simvastatin significantly reduced serum total cholesterol (TC) levels and low-density lipoprotein cholesterol (LDL-C) levels. However, the percentage reduction in TC levels was significantly greater with simvastatin than with pravastatin (−19 ± 7% vs −15 ± 9%, respectively; P P P 1c . No abnormal laboratory test results or adverse events were reported during treatment with either drug. Because both pravastatin and simvastatin significantly reduced TC and LDL-C levels without influencing control of blood glucose level, these drugs, especially simvastatin, might be safe and useful for treating hyperlipidemic patients with type 2 diabetes mellitus." @default.
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- W2079690248 date "1999-07-01" @default.
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- W2079690248 title "Pravastatin versus simvastatin in hyperlipidemic patients with type 2 diabetes mellitus" @default.
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- W2079690248 doi "https://doi.org/10.1016/s0011-393x(99)80019-8" @default.
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