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- W2079727114 abstract "The association of a particular human leukocyte antigen (HL4) determinant with multiple sclerosis (MS) was first described in 1972 (Bertrams et al, Tksue Antigens 1972, 2~405-408; Maito et al, Ts Jersild et al, L.ancet 1973, i&1221-1225). The association with HLADR2 was also ev ident in black American patients (DuPont et al, J Neurol Sci 1977, 43:1!+26). In addition, a distinction was made in Australian patients between benign exacerbating/remitting MS of early onset, associated with the haplotype HLA-43, B7, DR2 and more severe, progressive MS of later onset, associated with the haplotype HLA-Al, B8, DR3 [ 11. In other populations, different haplotypes have been associated with the disease. For example, HLADR4 is increased with MS in Jordanian Arab MS populations (Kurdi et al, Luncet 1977, i:l1231125). HIADRw6 is increased in Japanese (Naito et al, Tissue Antigens 1978, 12:19-24) and Mexican MS populations (Gorodezky et al, Hum Immunoll986,16:364-374). In Italian patients, both DR2 (Mattiuz et al, Report of the 8th H&tocompatibili(y Workshop, 1980) and DR4 (Bodmer et al., Report of the 7th H&xompatibillity Workshop, 1977) frequencies were reported to be increased in MS. All these associations are, however, relatively weak and need to be confirmed in larger studies. No D and DR antigens were found to be significantly associated with MS in Israeli Jews (Brautbar et al, Tksue Antigens 1982, 19:18+197)." @default.
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- W2079727114 title "The role of the MHC and T-cell receptor in susceptibility to multiple sclerosis" @default.
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- W2079727114 doi "https://doi.org/10.1016/0952-7915(90)90021-8" @default.
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