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• W2079733660 abstract "MicroRNAs influence cell physiology; alteration in miRNA regulation can be implicated in carcinogenesis and disease progression. Generally, one miRNA is predicted to regulate several hundred genes, and as a result, miRNAs could serve as a better classifier than gene expression. We combine validated miRNA expression values with imaging features to classify NSCLC brain mets from non-brain mets and identify possible biomarkers of brain mets. This research involves comprehensive miRNA expression profiling, evaluation of normalisation techniques and combination of miRNA with imaging features FDG-PET/CT and CT Scan. The biomarkers were validated on an independent data set to predict potential brain mets." @default.
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• W2079733660 date "2011-01-01" @default.
• W2079733660 modified "2023-10-15" @default.
• W2079733660 title "Biomarkers associated with metastasis of lung cancer to brain predict patient survival" @default.
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• W2079733660 doi "https://doi.org/10.1504/ijdmb.2011.040385" @default.
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