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- W2079736681 abstract "A SIGNIFICANT reduction in the incidence of pneumococcal endocarditis has occurred since the introduction of penicillin. Though 15% of Thayer's<sup>1</sup>536 cases of endocarditis prior to 1931 were caused by pneumococci, recently published series<sup>2,3</sup>indicate that the pneumococcus now accounts for less than 3% of all cases. Though pneumococcal endocarditis was with rare exceptions invariably a disease of hopeless prognosis<sup>4,5</sup>before the discovery of penicillin, evaluation of the impact of penicillin therapy upon prognosis has been hampered by the low incidence of the disease. The present report is based on a study of 15 cases of penicillin-treated pneumococcal endocarditis seen at the Cincinnati General Hospital during the last 20 years. In addition, 29 cases from the English literature are reviewed. <h3>Clinical Material</h3> The records of all cases of pneumococcal endocarditis at the Cincinnati General Hospital from 1945 to 1965 were reviewed. The diagnosis of endocarditis was established" @default.
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- W2079736681 date "1966-09-01" @default.
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- W2079736681 title "Pneumococcal Endocarditis in the Penicillin Era" @default.
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- W2079736681 doi "https://doi.org/10.1001/archinte.1966.00290150004003" @default.
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