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• W2079742829 endingPage "1077" @default.
• W2079742829 startingPage "1069" @default.
• W2079742829 abstract "Background context Nerve fiber growth inside the degenerative intervertebral discs and facets is thought to be a source of pain, although there may be several other pathological and clinical reasons for the neck pain. It, however, remains difficult to decipher how much disc and facet joints contribute to overall degenerative segmental responses. Although the biomechanical effects of disc degeneration (DD) on segmental flexibility and posterior facets have been reported in the lumbar spine, a clear understanding of the pathways of degenerative progression is still lacking in the cervical spine. Purpose To test the hypothesis that after an occurrence of degenerative disease in a cervical disc, changes in the facet loads will be higher than changes in the disc pressure. Study design To understand the biomechanical relationships between segmental flexibility, disc pressure, and facet loads when the C5–C6 disc degenerates. Methods A poroelastic, three-dimensional finite element (FE) model of a normal C5–C6 segment was developed and validated. Two degenerated disc models (moderate and severe) were built from the normal disc model. Biomechanical responses of the three FE models (normal, moderate, and severe) were further studied under diurnal compression (at the end of the daytime activity period) and moment loads (at the end of 5 seconds) in terms of disc height loss, angular motions, disc pressure, and facet loads (average of right and left facets). Results Disc deformation under compression and segmental rotational motions under moment loads for the normal disc model agreed well with the corresponding in vivo studies. A decrease in segmental flexibility because of DD is accompanied by a decrease in disc pressure and an increase in facet loads. Biomechanical effects of degenerative disc changes are least in flexion. Segmental flexibility changes are higher in extension, whereas changes in disc pressure and facet loads are higher in lateral bending and axial rotation, respectively. Conclusions The results of the present study confirmed the hypothesis of higher changes in facet loads than in disc pressure, suggesting posterior facets are more affected than discs because of a decrease in degenerative segmental flexibility. Therefore, a degenerated disc may increase the risk of overloading the posterior facet joints. It should be clearly noted that only after degeneration simulation in the disc, we recorded the biomechanical responses of the facets and disc. Therefore, our hypothesis does not suggest that facet joint osteoarthritis may occur before degeneration in the disc. Future cervical spine–based experiments are warranted to verify the conclusions presented in this study." @default.
• W2079742829 created "2016-06-24" @default.
• W2079742829 creator A5004582302 @default.
• W2079742829 creator A5026974503 @default.
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• W2079742829 creator A5069437689 @default.
• W2079742829 date "2010-12-01" @default.
• W2079742829 modified "2023-10-15" @default.
• W2079742829 title "Reduction in segmental flexibility because of disc degeneration is accompanied by higher changes in facet loads than changes in disc pressure: a poroelastic C5–C6 finite element investigation" @default.
• W2079742829 cites W109367802 @default.
• W2079742829 cites W171823573 @default.
• W2079742829 cites W1781745458 @default.
• W2079742829 cites W1972411277 @default.
• W2079742829 cites W1972923344 @default.
• W2079742829 cites W1976556135 @default.
• W2079742829 cites W1980151235 @default.
• W2079742829 cites W1981187524 @default.
• W2079742829 cites W1983817603 @default.
• W2079742829 cites W1992647292 @default.
• W2079742829 cites W1994714657 @default.
• W2079742829 cites W1995064303 @default.
• W2079742829 cites W1998726572 @default.
• W2079742829 cites W2000619737 @default.
• W2079742829 cites W2004549774 @default.
• W2079742829 cites W2006340675 @default.
• W2079742829 cites W2007446525 @default.
• W2079742829 cites W2012101167 @default.
• W2079742829 cites W2018012095 @default.
• W2079742829 cites W2019008012 @default.
• W2079742829 cites W2020288024 @default.
• W2079742829 cites W2022790887 @default.
• W2079742829 cites W2023904315 @default.
• W2079742829 cites W2024695172 @default.
• W2079742829 cites W2025528234 @default.
• W2079742829 cites W2028253497 @default.
• W2079742829 cites W2028725423 @default.
• W2079742829 cites W2030105831 @default.
• W2079742829 cites W2030516848 @default.
• W2079742829 cites W2030574593 @default.
• W2079742829 cites W2030853444 @default.
• W2079742829 cites W2031780226 @default.
• W2079742829 cites W2032306392 @default.
• W2079742829 cites W2035554074 @default.
• W2079742829 cites W2041142971 @default.
• W2079742829 cites W2042352469 @default.
• W2079742829 cites W2042554067 @default.
• W2079742829 cites W2045461940 @default.
• W2079742829 cites W2047413249 @default.
• W2079742829 cites W2048443703 @default.
• W2079742829 cites W2049593438 @default.
• W2079742829 cites W2055082928 @default.
• W2079742829 cites W2056068773 @default.
• W2079742829 cites W2060068739 @default.
• W2079742829 cites W2063504999 @default.
• W2079742829 cites W2063518237 @default.
• W2079742829 cites W2066422769 @default.
• W2079742829 cites W2068541767 @default.
• W2079742829 cites W2068559315 @default.
• W2079742829 cites W2069474795 @default.
• W2079742829 cites W2072158777 @default.
• W2079742829 cites W2073598437 @default.
• W2079742829 cites W2076451398 @default.
• W2079742829 cites W2077205535 @default.
• W2079742829 cites W2077836245 @default.
• W2079742829 cites W2079408170 @default.
• W2079742829 cites W2079935767 @default.
• W2079742829 cites W2081071621 @default.
• W2079742829 cites W2083652071 @default.
• W2079742829 cites W2084532170 @default.
• W2079742829 cites W2086301811 @default.
• W2079742829 cites W2086839429 @default.
• W2079742829 cites W2087075348 @default.
• W2079742829 cites W2088923877 @default.
• W2079742829 cites W2089018638 @default.
• W2079742829 cites W2090077377 @default.
• W2079742829 cites W2092071763 @default.
• W2079742829 cites W2105396637 @default.
• W2079742829 cites W2112219615 @default.
• W2079742829 cites W2118855121 @default.
• W2079742829 cites W2120618315 @default.
• W2079742829 cites W2122482878 @default.
• W2079742829 cites W2134381361 @default.
• W2079742829 cites W2139890181 @default.
• W2079742829 cites W2158265544 @default.
• W2079742829 cites W2166181947 @default.
• W2079742829 cites W2166759700 @default.
• W2079742829 cites W2166991885 @default.
• W2079742829 cites W2214743382 @default.
• W2079742829 cites W2326699250 @default.
• W2079742829 cites W2342571638 @default.
• W2079742829 cites W2397455496 @default.
• W2079742829 cites W4301894995 @default.
• W2079742829 cites W4317526547 @default.
• W2079742829 doi "https://doi.org/10.1016/j.spinee.2010.09.012" @default.
• W2079742829 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/21094468" @default.
• W2079742829 hasPublicationYear "2010" @default.
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