Matches in SemOpenAlex for { <https://semopenalex.org/work/W2079744026> ?p ?o ?g. }
Showing items 1 to 68 of
68
with 100 items per page.
- W2079744026 abstract "Abstract Poly(ethylenimine) (PEI) was modified by laurylation, introduction of 4- N , N -di(3-carboxy-propyl)aminopyridyl (DAP) group, Ni II -template condensation of the polymer with glyoxal, and/or acetylation of primary and secondary amines, to produce Ni 1 II [Lau 11 -PEI-GO-DAP 5 ]Ac and several other related derivatives of PEI. The hydrolysis of anionic ester 2-nitro-4-carboxyphenyl acetate (NCPA) and hydrophobic ester 4-nitrophenyl caproate (NPC) was effectively catalyzed by Ni 1 II [Lau 11 -PEI-GO-DAP 5 ]Ac and turnover kinetics due to regeneration of the catalyst was observed. Artificial metalloesterase Ni 1 II [Lau 11 -PEI-GO-DAP 5 ]Ac manifested characteristics of actions of metalloenzymes such as complex formation with substrates, considerable degree of catalysis, selectivity toward hydrophobic or anionic esters, and cooperativity among multiple catalytic elements including metal ions. In the hydrolysis of NCPA, the metal center anchors the anionic ester and the DAP moiety makes nucleophilic attack at the bound substrate. Electrostatic attraction between the metal center and NCPA is strengthened by the hydrophobic microenvironment provided by the lauryl groups. In the hydrolysis of NPC, the substrate is bound by the catalyst primarily due to the hydrophobic effects exerted by the lauryl groups and the DAP moiety makes nucleophilic attack at the bound substrate. In NPC hydrolysis, the intrinsic nucleophilicity of the DAP is enhanced by the medium effects exerted by the macrocyclic metal centers." @default.
- W2079744026 created "2016-06-24" @default.
- W2079744026 creator A5041629005 @default.
- W2079744026 creator A5079172829 @default.
- W2079744026 date "1994-03-01" @default.
- W2079744026 modified "2023-10-07" @default.
- W2079744026 title "Cooperation of Macrocyclic Metal Centers with 4-Dialkylaminopyridines in Catalysis by Poly(ethylenimine)-Based Artificial Metalloesterases" @default.
- W2079744026 doi "https://doi.org/10.1006/bioo.1994.1007" @default.
- W2079744026 hasPublicationYear "1994" @default.
- W2079744026 type Work @default.
- W2079744026 sameAs 2079744026 @default.
- W2079744026 citedByCount "10" @default.
- W2079744026 crossrefType "journal-article" @default.
- W2079744026 hasAuthorship W2079744026A5041629005 @default.
- W2079744026 hasAuthorship W2079744026A5079172829 @default.
- W2079744026 hasConcept C111368507 @default.
- W2079744026 hasConcept C127313418 @default.
- W2079744026 hasConcept C155647269 @default.
- W2079744026 hasConcept C161790260 @default.
- W2079744026 hasConcept C178790620 @default.
- W2079744026 hasConcept C178907741 @default.
- W2079744026 hasConcept C185592680 @default.
- W2079744026 hasConcept C188027245 @default.
- W2079744026 hasConcept C21951064 @default.
- W2079744026 hasConcept C2776568683 @default.
- W2079744026 hasConcept C2777289219 @default.
- W2079744026 hasConcept C544153396 @default.
- W2079744026 hasConcept C94412978 @default.
- W2079744026 hasConceptScore W2079744026C111368507 @default.
- W2079744026 hasConceptScore W2079744026C127313418 @default.
- W2079744026 hasConceptScore W2079744026C155647269 @default.
- W2079744026 hasConceptScore W2079744026C161790260 @default.
- W2079744026 hasConceptScore W2079744026C178790620 @default.
- W2079744026 hasConceptScore W2079744026C178907741 @default.
- W2079744026 hasConceptScore W2079744026C185592680 @default.
- W2079744026 hasConceptScore W2079744026C188027245 @default.
- W2079744026 hasConceptScore W2079744026C21951064 @default.
- W2079744026 hasConceptScore W2079744026C2776568683 @default.
- W2079744026 hasConceptScore W2079744026C2777289219 @default.
- W2079744026 hasConceptScore W2079744026C544153396 @default.
- W2079744026 hasConceptScore W2079744026C94412978 @default.
- W2079744026 hasLocation W20797440261 @default.
- W2079744026 hasOpenAccess W2079744026 @default.
- W2079744026 hasPrimaryLocation W20797440261 @default.
- W2079744026 hasRelatedWork W157118698 @default.
- W2079744026 hasRelatedWork W1991831490 @default.
- W2079744026 hasRelatedWork W1995773608 @default.
- W2079744026 hasRelatedWork W1995969311 @default.
- W2079744026 hasRelatedWork W1998346484 @default.
- W2079744026 hasRelatedWork W2000052144 @default.
- W2079744026 hasRelatedWork W2002531183 @default.
- W2079744026 hasRelatedWork W2056521802 @default.
- W2079744026 hasRelatedWork W2061701227 @default.
- W2079744026 hasRelatedWork W2068131361 @default.
- W2079744026 hasRelatedWork W2078091073 @default.
- W2079744026 hasRelatedWork W2086725202 @default.
- W2079744026 hasRelatedWork W2086992154 @default.
- W2079744026 hasRelatedWork W2153665861 @default.
- W2079744026 hasRelatedWork W2316293345 @default.
- W2079744026 hasRelatedWork W2810333318 @default.
- W2079744026 hasRelatedWork W2951012319 @default.
- W2079744026 hasRelatedWork W3153244133 @default.
- W2079744026 hasRelatedWork W3160449533 @default.
- W2079744026 hasRelatedWork W782161988 @default.
- W2079744026 isParatext "false" @default.
- W2079744026 isRetracted "false" @default.
- W2079744026 magId "2079744026" @default.
- W2079744026 workType "article" @default.