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• W2079744131 abstract "Single functional human CuZnSOD gene encodes two species of mRNA differing in size by 200 nucleotides in the 3'-untranslated region (UTR). We studied the expression of the CuZnSOD cDNA with different 3'- and 5'-UTR. Deletion in the 5'-end does not affect the expression of the enzyme, however, deletion in the 3'-UTR decreases the level of expression of CuZnSOD. The plasmids containing the long CuZnSOD cDNA with all polyadenylation signal sequences utilize primarily the last polyadenylation site and give a long mRNA, which produces three times more enzyme than the short mRNA lacking the last polyadenylation site and the AU-rich region." @default.
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• W2079744131 date "1995-04-10" @default.
• W2079744131 modified "2023-09-26" @default.
• W2079744131 title "Human CuZn superoxide dismutase enzymatic activity in cells is regulated by the length of the mRNA" @default.
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• W2079744131 doi "https://doi.org/10.1016/0014-5793(95)00266-c" @default.
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