FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2079744186> ?p ?o ?g. }

• W2079744186 endingPage "447" @default.
• W2079744186 startingPage "441" @default.
• W2079744186 abstract "The expression of the p73 gene and the methylation status was examined in 61 acute lymphoblastic leukemia (ALL) cell lines and lymphocytes from seven healthy individuals. p73 mRNA was not expressed in 19 (31.1%) of 61 ALL cell lines, including 11 (31.4%) of 35 B-precursor ALL cell lines, 2 (16.7%) of 12 B-ALL/Burkitt lymphoma (BL) cell lines (totally 27.7% of B-lineage cell lines), 6 (42.9%) of 14 T-ALL cell lines, and expressed in all of normal lymphocytes, by reverse transcriptase-polymerase chain reaction (RT-PCR). Restriction-enzyme related PCR (REP) and methylation-specific PCR (MSP) revealed that the cell lines lacking p73 mRNA expression were hypermethylated. In contrast, normal lymphocytes and most cell lines that expressed detectable p73 mRNA were not hypermethylated with the exception of five cell lines. Furthermore, bisulfite genomic sequencing confirmed the results obtained by REP and MSP. Our results suggest that p73 inactivation may be involved in the pathogenesis of both T- and B-ALLs, and that hypermethylation is the predominant mechanism of inactivation of the p73 gene in ALL." @default.
• W2079744186 created "2016-06-24" @default.
• W2079744186 creator A5003916483 @default.
• W2079744186 creator A5031826187 @default.
• W2079744186 creator A5034962322 @default.
• W2079744186 creator A5036006370 @default.
• W2079744186 creator A5054303171 @default.
• W2079744186 creator A5056097253 @default.
• W2079744186 creator A5058270280 @default.
• W2079744186 creator A5078968582 @default.
• W2079744186 creator A5087489183 @default.
• W2079744186 creator A5087756926 @default.
• W2079744186 date "2001-06-01" @default.
• W2079744186 modified "2023-10-17" @default.
• W2079744186 title "Loss of p73 gene expression in lymphoid leukemia cell lines is associated with hypermethylation" @default.
• W2079744186 cites W1553314463 @default.
• W2079744186 cites W1786259862 @default.
• W2079744186 cites W191043282 @default.
• W2079744186 cites W1964620315 @default.
• W2079744186 cites W1975812358 @default.
• W2079744186 cites W1975924585 @default.
• W2079744186 cites W1978469902 @default.
• W2079744186 cites W1982121839 @default.
• W2079744186 cites W1985064409 @default.
• W2079744186 cites W1994465394 @default.
• W2079744186 cites W1994877506 @default.
• W2079744186 cites W1997837993 @default.
• W2079744186 cites W2011497780 @default.
• W2079744186 cites W2064032164 @default.
• W2079744186 cites W2075621444 @default.
• W2079744186 cites W2084118479 @default.
• W2079744186 cites W2114343987 @default.
• W2079744186 cites W2150162153 @default.
• W2079744186 cites W2312368952 @default.
• W2079744186 cites W2325129660 @default.
• W2079744186 cites W2333707271 @default.
• W2079744186 cites W2400514435 @default.
• W2079744186 cites W4210997484 @default.
• W2079744186 doi "https://doi.org/10.1016/s0145-2126(00)00148-x" @default.
• W2079744186 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/11337015" @default.
• W2079744186 hasPublicationYear "2001" @default.
• W2079744186 type Work @default.
• W2079744186 sameAs 2079744186 @default.
• W2079744186 citedByCount "46" @default.
• W2079744186 countsByYear W20797441862012 @default.
• W2079744186 countsByYear W20797441862015 @default.
• W2079744186 countsByYear W20797441862021 @default.
• W2079744186 crossrefType "journal-article" @default.
• W2079744186 hasAuthorship W2079744186A5003916483 @default.
• W2079744186 hasAuthorship W2079744186A5031826187 @default.
• W2079744186 hasAuthorship W2079744186A5034962322 @default.
• W2079744186 hasAuthorship W2079744186A5036006370 @default.
• W2079744186 hasAuthorship W2079744186A5054303171 @default.
• W2079744186 hasAuthorship W2079744186A5056097253 @default.
• W2079744186 hasAuthorship W2079744186A5058270280 @default.
• W2079744186 hasAuthorship W2079744186A5078968582 @default.
• W2079744186 hasAuthorship W2079744186A5087489183 @default.
• W2079744186 hasAuthorship W2079744186A5087756926 @default.
• W2079744186 hasConcept C104317684 @default.
• W2079744186 hasConcept C150194340 @default.
• W2079744186 hasConcept C153911025 @default.
• W2079744186 hasConcept C156719811 @default.
• W2079744186 hasConcept C189235521 @default.
• W2079744186 hasConcept C190727270 @default.
• W2079744186 hasConcept C2778461978 @default.
• W2079744186 hasConcept C2779469565 @default.
• W2079744186 hasConcept C33288867 @default.
• W2079744186 hasConcept C49105822 @default.
• W2079744186 hasConcept C502942594 @default.
• W2079744186 hasConcept C54355233 @default.
• W2079744186 hasConcept C81885089 @default.
• W2079744186 hasConcept C86803240 @default.
• W2079744186 hasConceptScore W2079744186C104317684 @default.
• W2079744186 hasConceptScore W2079744186C150194340 @default.
• W2079744186 hasConceptScore W2079744186C153911025 @default.
• W2079744186 hasConceptScore W2079744186C156719811 @default.
• W2079744186 hasConceptScore W2079744186C189235521 @default.
• W2079744186 hasConceptScore W2079744186C190727270 @default.
• W2079744186 hasConceptScore W2079744186C2778461978 @default.
• W2079744186 hasConceptScore W2079744186C2779469565 @default.
• W2079744186 hasConceptScore W2079744186C33288867 @default.
• W2079744186 hasConceptScore W2079744186C49105822 @default.
• W2079744186 hasConceptScore W2079744186C502942594 @default.
• W2079744186 hasConceptScore W2079744186C54355233 @default.
• W2079744186 hasConceptScore W2079744186C81885089 @default.
• W2079744186 hasConceptScore W2079744186C86803240 @default.
• W2079744186 hasFunder F4320320912 @default.
• W2079744186 hasFunder F4320321945 @default.
• W2079744186 hasIssue "6" @default.
• W2079744186 hasLocation W20797441861 @default.
• W2079744186 hasLocation W20797441862 @default.
• W2079744186 hasOpenAccess W2079744186 @default.
• W2079744186 hasPrimaryLocation W20797441861 @default.
• W2079744186 hasRelatedWork W1998349112 @default.
• W2079744186 hasRelatedWork W2024490794 @default.
• W2079744186 hasRelatedWork W2046964473 @default.
• W2079744186 hasRelatedWork W2052355316 @default.
• W2079744186 hasRelatedWork W2054863651 @default.

• next