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• W2079745413 abstract "Decreasing latitude and increasing frequency of population lactase nonpersistence have been reported to diminish risks for several diseases, but the reason for overlap has not been explained. We evaluate, relationships between calculated national annual ultraviolet light B (UVB) exposure, latitude, and national lactose digestion frequencies. Annual UVB exposure and latitude were based on weighted averages from several cities in different countries. Lactase distribution status was based on published data that have been used previously to derive relations with diseases. We compare univariate regression analyses (r(2)(adj), slope) of percentage of lactase nonpersistence with UVB or latitude. We determine, differences between European and non-European sources by multiregression analysis of independent variables. Correlation between UVB and latitude is high (r(2) = 0.89), and between percentage of lactase nonpersistence and either latitude or UVB the correlation is moderately strong with r(2) = 0.51 and 0.46, respectively, with P ≤ 0.01 for both. A more detailed analysis shows that correlations between percentage of lactase nonpersistence and UVB are only significant in Europe, r(2) = 0.59, P < 0.001, whereas outside Europe: r(2) = 0.06, P = 0.16. These relationships raise hypothetical explanations to account for the observed overlap in similar risk modification by the 2 variables." @default.
• W2079745413 created "2016-06-24" @default.
• W2079745413 creator A5027244714 @default.
• W2079745413 creator A5032845986 @default.
• W2079745413 creator A5034465718 @default.
• W2079745413 creator A5063971915 @default.
• W2079745413 date "2011-10-01" @default.
• W2079745413 modified "2023-09-27" @default.
• W2079745413 title "Significant Positive Correlation Between Sunshine and Lactase Nonpersistence in Europe May Implicate Both in Similarly Altering Risks for Some Diseases" @default.
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• W2079745413 doi "https://doi.org/10.1080/01635581.2011.596641" @default.
• W2079745413 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/21800978" @default.
• W2079745413 hasPublicationYear "2011" @default.
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