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- W2079748132 abstract "TOTAL joint replacement has been accepted as effective treatment for painful arthritis by the medical community. Indeed, between 1972 and 1976, an estimated 0.5 million joint prostheses were implanted in the United States.<sup>1</sup>Infection of a prosthesis is one of the most serious complications of total joint replacement and is associated with serious morbidity and mortality.<sup>2,3</sup>The pathogenesis of this infection, including portals of bacterial entry, is currently under debate, but evidence is accumulating to suggest that organisms are introduced by two routes: first, by local contamination at the time of surgery,<sup>4</sup>and later, by the hematogenous route.<sup>5-7</sup>Prophylactic antibiotics and local wound care precautions can substantially reduce the incidence of early infections, but appear to have little effect on late sepsis.<sup>8</sup>We report here a case of<i>Staphylococcus aureus</i>hip sepsis occurring five years after total hip replacement, in association with an infected ulcer" @default.
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- W2079748132 date "1979-11-16" @default.
- W2079748132 modified "2023-10-18" @default.
- W2079748132 title "Hematogenous Infection in Total Joint Replacement" @default.
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- W2079748132 doi "https://doi.org/10.1001/jama.1979.03300200043023" @default.
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