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• W2079748807 abstract "El trasplante hepático es el tratamiento de elección de las enfermedades hepáticas crónicas descompensadas. La disparidad en el número de órganos donantes y potenciales receptores condiciona una notable mortalidad pretrasplante que obliga a una óptima racionalización en la asignación de órganos. El MELD (Model for End-stage Liver Disease) es un índice pronóstico de mortalidad objetivo y fácilmente reproducible, basado en tres variables analíticas simples: la bilirrubina, la creatinina sérica y el cociente internacional normalizado del tiempo de protrombina (INR). La implementación del MELD como sistema de asignación de órganos ha disminuido la mortalidad en lista de espera sin afectar la supervivencia postrasplante. No obstante, el MELD tiene algunas limitaciones que obligan a seguir mejorando el sistema de asignación de prioridad en lista de espera de trasplante hepático. Liver transplantation is the most effective treatment for many patients with chronic end-stage liver disease. The discrepancy between the number of donor organs and potential recipients causes marked pre-transplantation mortality and consequently optimal rationalization of organ allocation is essential. The Model for End-Stage Liver Disease (MELD) is an objective and easily reproducible prognostic index of mortality based on three simple analytical variables: bilirubin and serum creatinine and the prothrombin time/International Normalized Ratio (INR) of protrombine time. The implementation of MELD as an organ allocation system has reduced mortality on the waiting list without affecting post-transplantation survival. Nevertheless, this model has some limitations and consequently further investigations should be performed to improve the organ allocation policy in liver transplantation." @default.
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• W2079748807 date "2010-04-01" @default.
• W2079748807 modified "2023-10-07" @default.
• W2079748807 title "Utilidad del MELD (Model for End-stage Liver Disease) para asignar prioridades en el trasplante hepático" @default.
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• W2079748807 doi "https://doi.org/10.1016/j.gastrohep.2009.04.007" @default.
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