FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2079752502> ?p ?o ?g. }

• W2079752502 abstract "A previous investigation in our laboratory found that the stimulus effects of the 5-HT2A agonist, LSD, are potentiated by 5-HT1A receptor agonists including the prototypic agonist, 8-OH-DPAT. Also suggestive of behaviorally relevant interactions between 5-HT1A and 5-HT2A receptors are behavioral analyses of locomotor activity, head-twitch response, forepaw treading and production of the serotonin syndrome; in some instances effects are augmented, in other, diminished. These observations led us in the present investigation to test the hypothesis that stimulus control by 8-OH-DPAT [0.2 mg/kg; 15 min pretreatment time] is modulated by 5-HT2A ligands. Stimulus control was established with 8-OH-DPAT in a group of 10 rats. A two-lever, fixed ratio 10, positively reinforced task with saline controls was employed. As shown previously, stimulus control by 8-OH-DPAT and the generalization of 8-OH-DPAT to the 5-HT1A partial agonist, buspirone, was completely blocked by the selective 5-HT1A antagonist, WAY-100635. In contrast, antagonism by the selective 5-HT2A antagonist, M100907 [0.1 mg/kg; 30 min pretreatment time], of 8-OH-DPAT and of the generalization of 8-OH-DPAT to buspirone was statistically significant but less than complete. In light of our previous conclusions regarding the interactions of 5-HT1A agonists with LSD-induced stimulus control, the present data suggest that the interaction between 5-HT1A and 5-HT2A receptors is bidirectional in drug discrimination studies." @default.
• W2079752502 created "2016-06-24" @default.
• W2079752502 creator A5007245676 @default.
• W2079752502 creator A5010350536 @default.
• W2079752502 creator A5041625201 @default.
• W2079752502 creator A5065486287 @default.
• W2079752502 creator A5072565784 @default.
• W2079752502 date "2008-01-01" @default.
• W2079752502 modified "2023-09-27" @default.
• W2079752502 title "The stimulus effects of 8-OH-DPAT: Evidence for a 5-HT2A receptor-mediated component" @default.
• W2079752502 cites W1558293110 @default.
• W2079752502 cites W1809659791 @default.
• W2079752502 cites W1877874868 @default.
• W2079752502 cites W1895729847 @default.
• W2079752502 cites W1904151292 @default.
• W2079752502 cites W1927413935 @default.
• W2079752502 cites W1956361529 @default.
• W2079752502 cites W1963690073 @default.
• W2079752502 cites W1970514465 @default.
• W2079752502 cites W1972075343 @default.
• W2079752502 cites W1977832150 @default.
• W2079752502 cites W1981862550 @default.
• W2079752502 cites W1994153884 @default.
• W2079752502 cites W1995977418 @default.
• W2079752502 cites W2001928694 @default.
• W2079752502 cites W20065136 @default.
• W2079752502 cites W2010245569 @default.
• W2079752502 cites W2017392759 @default.
• W2079752502 cites W2022909733 @default.
• W2079752502 cites W2023748980 @default.
• W2079752502 cites W2025505082 @default.
• W2079752502 cites W2029267570 @default.
• W2079752502 cites W2031421864 @default.
• W2079752502 cites W2032646493 @default.
• W2079752502 cites W2033559729 @default.
• W2079752502 cites W2034861313 @default.
• W2079752502 cites W2038393570 @default.
• W2079752502 cites W2050034089 @default.
• W2079752502 cites W2054722815 @default.
• W2079752502 cites W2055054184 @default.
• W2079752502 cites W2055707656 @default.
• W2079752502 cites W2057478907 @default.
• W2079752502 cites W2057561126 @default.
• W2079752502 cites W2058092335 @default.
• W2079752502 cites W2058637803 @default.
• W2079752502 cites W2066663898 @default.
• W2079752502 cites W2068033513 @default.
• W2079752502 cites W2068616309 @default.
• W2079752502 cites W2082394649 @default.
• W2079752502 cites W2083916652 @default.
• W2079752502 cites W2084450927 @default.
• W2079752502 cites W2089880141 @default.
• W2079752502 cites W2094569992 @default.
• W2079752502 cites W2095213614 @default.
• W2079752502 cites W2107985334 @default.
• W2079752502 cites W2121264019 @default.
• W2079752502 cites W2123354702 @default.
• W2079752502 cites W2124291611 @default.
• W2079752502 cites W2127165654 @default.
• W2079752502 cites W2148608081 @default.
• W2079752502 cites W2164892563 @default.
• W2079752502 cites W2399939699 @default.
• W2079752502 cites W2406417215 @default.
• W2079752502 cites W2414246970 @default.
• W2079752502 cites W62757096 @default.
• W2079752502 doi "https://doi.org/10.1016/j.pbb.2007.09.011" @default.
• W2079752502 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/2322851" @default.
• W2079752502 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/17936346" @default.
• W2079752502 hasPublicationYear "2008" @default.
• W2079752502 type Work @default.
• W2079752502 sameAs 2079752502 @default.
• W2079752502 citedByCount "5" @default.
• W2079752502 countsByYear W20797525022012 @default.
• W2079752502 countsByYear W20797525022018 @default.
• W2079752502 countsByYear W20797525022020 @default.
• W2079752502 crossrefType "journal-article" @default.
• W2079752502 hasAuthorship W2079752502A5007245676 @default.
• W2079752502 hasAuthorship W2079752502A5010350536 @default.
• W2079752502 hasAuthorship W2079752502A5041625201 @default.
• W2079752502 hasAuthorship W2079752502A5065486287 @default.
• W2079752502 hasAuthorship W2079752502A5072565784 @default.
• W2079752502 hasBestOaLocation W20797525022 @default.
• W2079752502 hasConcept C126322002 @default.
• W2079752502 hasConcept C134018914 @default.
• W2079752502 hasConcept C15744967 @default.
• W2079752502 hasConcept C169760540 @default.
• W2079752502 hasConcept C170493617 @default.
• W2079752502 hasConcept C185592680 @default.
• W2079752502 hasConcept C26760741 @default.
• W2079752502 hasConcept C2775864247 @default.
• W2079752502 hasConcept C2776238416 @default.
• W2079752502 hasConcept C2776885963 @default.
• W2079752502 hasConcept C2777287423 @default.
• W2079752502 hasConcept C2778938600 @default.
• W2079752502 hasConcept C2779547902 @default.
• W2079752502 hasConcept C2779918689 @default.
• W2079752502 hasConcept C2781093953 @default.
• W2079752502 hasConcept C3018514133 @default.
• W2079752502 hasConcept C53910766 @default.
• W2079752502 hasConcept C542102704 @default.

• next