FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2079753417> ?p ?o ?g. }

• W2079753417 endingPage "525" @default.
• W2079753417 startingPage "518" @default.
• W2079753417 abstract "The relationships of the electrical to the mechanical responses of the canine trachealis muscle during stimulation of its cholinergic nerves or exposure to exogenous acetylcholine were recorded in the single or the double sucrose gap. At 27 degrees C, the responses to a train of stimuli consisted of a transient depolarization excitatory junction potential of 10-30 mV followed by fading oscillations and contractions. When stimulus parameters were varied in the single sucrose gap, contractions were more closely associated with the occurrence of and varied in duration with the oscillations rather than with the amplitude of the EJP. Acetylcholine superfused at a concentration of 10(-6) M for 30 s caused a prolonged depolarization of 10-20 mV, but a much larger contraction than could be elicited by nerve stimulation. None of the responses to acetylcholine was significantly affected by the Ca channel antagonists, nifedipine, nitrendipine, or verapamil in Ca channel blocking concentrations. When tissues were exposed to a Ca-free medium, the excitatory junction potentials and oscillations rapidly disappeared, but the electrical and mechanical responses to acetylcholine persisted and only gradually disappeared with repetitive exposures. Furthermore, in a medium with normal Ca2+ in the double sucrose gap, depolarization by 10-15 mV with an applied current caused no contraction, and repolarization to the normal membrane potential during acetylcholine-induced contraction caused no relaxation. Tetraethylammonium ion (20 mM) depolarized the membrane, increased membrane resistance, and enhanced the secondary oscillations and contractions after field stimulation. No other K(+)-channel blocker tested (Ba2+, apamin, 4-aminopyridine, glibenclamide, charybdotoxin) had the effect of prolonging secondary oscillations.(ABSTRACT TRUNCATED AT 250 WORDS)" @default.
• W2079753417 created "2016-06-24" @default.
• W2079753417 creator A5001504723 @default.
• W2079753417 creator A5030854659 @default.
• W2079753417 creator A5040999488 @default.
• W2079753417 creator A5052792869 @default.
• W2079753417 date "1991-04-01" @default.
• W2079753417 modified "2023-09-26" @default.
• W2079753417 title "Role of depolarization and calcium in contractions of canine trachealis from endogenous or exogenous acetylcholine" @default.
• W2079753417 cites W1531683217 @default.
• W2079753417 cites W1866600283 @default.
• W2079753417 cites W1975705594 @default.
• W2079753417 cites W2013051600 @default.
• W2079753417 cites W2030169110 @default.
• W2079753417 cites W2046878259 @default.
• W2079753417 cites W2100436382 @default.
• W2079753417 cites W2108258922 @default.
• W2079753417 cites W2335174587 @default.
• W2079753417 cites W2376858370 @default.
• W2079753417 cites W2410030361 @default.
• W2079753417 cites W2410816254 @default.
• W2079753417 cites W2418548141 @default.
• W2079753417 doi "https://doi.org/10.1139/y91-078" @default.
• W2079753417 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/2059914" @default.
• W2079753417 hasPublicationYear "1991" @default.
• W2079753417 type Work @default.
• W2079753417 sameAs 2079753417 @default.
• W2079753417 citedByCount "20" @default.
• W2079753417 countsByYear W20797534172013 @default.
• W2079753417 countsByYear W20797534172014 @default.
• W2079753417 countsByYear W20797534172019 @default.
• W2079753417 crossrefType "journal-article" @default.
• W2079753417 hasAuthorship W2079753417A5001504723 @default.
• W2079753417 hasAuthorship W2079753417A5030854659 @default.
• W2079753417 hasAuthorship W2079753417A5040999488 @default.
• W2079753417 hasAuthorship W2079753417A5052792869 @default.
• W2079753417 hasConcept C112592302 @default.
• W2079753417 hasConcept C12554922 @default.
• W2079753417 hasConcept C126322002 @default.
• W2079753417 hasConcept C134018914 @default.
• W2079753417 hasConcept C153461711 @default.
• W2079753417 hasConcept C170493617 @default.
• W2079753417 hasConcept C178790620 @default.
• W2079753417 hasConcept C181911157 @default.
• W2079753417 hasConcept C185592680 @default.
• W2079753417 hasConcept C202870285 @default.
• W2079753417 hasConcept C2775910092 @default.
• W2079753417 hasConcept C2776919887 @default.
• W2079753417 hasConcept C2777022698 @default.
• W2079753417 hasConcept C2780419564 @default.
• W2079753417 hasConcept C2781295685 @default.
• W2079753417 hasConcept C29852270 @default.
• W2079753417 hasConcept C4141045 @default.
• W2079753417 hasConcept C517785266 @default.
• W2079753417 hasConcept C519063684 @default.
• W2079753417 hasConcept C55493867 @default.
• W2079753417 hasConcept C71924100 @default.
• W2079753417 hasConcept C86803240 @default.
• W2079753417 hasConceptScore W2079753417C112592302 @default.
• W2079753417 hasConceptScore W2079753417C12554922 @default.
• W2079753417 hasConceptScore W2079753417C126322002 @default.
• W2079753417 hasConceptScore W2079753417C134018914 @default.
• W2079753417 hasConceptScore W2079753417C153461711 @default.
• W2079753417 hasConceptScore W2079753417C170493617 @default.
• W2079753417 hasConceptScore W2079753417C178790620 @default.
• W2079753417 hasConceptScore W2079753417C181911157 @default.
• W2079753417 hasConceptScore W2079753417C185592680 @default.
• W2079753417 hasConceptScore W2079753417C202870285 @default.
• W2079753417 hasConceptScore W2079753417C2775910092 @default.
• W2079753417 hasConceptScore W2079753417C2776919887 @default.
• W2079753417 hasConceptScore W2079753417C2777022698 @default.
• W2079753417 hasConceptScore W2079753417C2780419564 @default.
• W2079753417 hasConceptScore W2079753417C2781295685 @default.
• W2079753417 hasConceptScore W2079753417C29852270 @default.
• W2079753417 hasConceptScore W2079753417C4141045 @default.
• W2079753417 hasConceptScore W2079753417C517785266 @default.
• W2079753417 hasConceptScore W2079753417C519063684 @default.
• W2079753417 hasConceptScore W2079753417C55493867 @default.
• W2079753417 hasConceptScore W2079753417C71924100 @default.
• W2079753417 hasConceptScore W2079753417C86803240 @default.
• W2079753417 hasIssue "4" @default.
• W2079753417 hasLocation W20797534171 @default.
• W2079753417 hasLocation W20797534172 @default.
• W2079753417 hasOpenAccess W2079753417 @default.
• W2079753417 hasPrimaryLocation W20797534171 @default.
• W2079753417 hasRelatedWork W1866600283 @default.
• W2079753417 hasRelatedWork W1972047684 @default.
• W2079753417 hasRelatedWork W1987718179 @default.
• W2079753417 hasRelatedWork W2035547334 @default.
• W2079753417 hasRelatedWork W2061007479 @default.
• W2079753417 hasRelatedWork W2076559485 @default.
• W2079753417 hasRelatedWork W2079753417 @default.
• W2079753417 hasRelatedWork W2088281397 @default.
• W2079753417 hasRelatedWork W2103909817 @default.
• W2079753417 hasRelatedWork W2141465268 @default.
• W2079753417 hasVolume "69" @default.
• W2079753417 isParatext "false" @default.
• W2079753417 isRetracted "false" @default.

• next