Matches in SemOpenAlex for { <https://semopenalex.org/work/W2079760460> ?p ?o ?g. }
Showing items 1 to 62 of
62
with 100 items per page.
- W2079760460 endingPage "148" @default.
- W2079760460 startingPage "141" @default.
- W2079760460 abstract "Lamberts SWJ, del Pozo E. Acute and long-term effects of SMS 201-995 in acromegaly.The subcutaneous administration of 50 μg SMS 201-995 at 0815 h in 18 acromegalic patients reduced plasma growth hormone (GH) levels from 2 to 6 h after injection from 36 ± 2 to 7 ± 1 μg/l (-80 ± 5%). Circulating GH concentrations had normalized to less than 5 μg/l during this period in 11 of 18 patients. Postprandial blood glucose levels after breakfast were significantly (p < 0.01) higher after SMS administration but significantly lower (p < 0.01) after supper. Chronic treatment of five acromegalic patients with 200-300 μg SMS 201-995 daily for 8-24 weeks resulted in a rapid clinical improvement in all patients and complete disappearance of the complaints in four of five patients. This was accompanied by tumour shrinkage as estimated by computerized tomography scanning in three of four patients. In parallel. mean plasma GH levels and serum somatomedin-C and phosphorus levels fell to or within the normal values. SMS 201-995 represents a new tool in the medical management of acromegaly and may become the treatment of choice, especially in patients who do not benefit sufficiently from surgery and/or radiotherapy." @default.
- W2079760460 created "2016-06-24" @default.
- W2079760460 creator A5012841131 @default.
- W2079760460 creator A5043165222 @default.
- W2079760460 date "1986-01-01" @default.
- W2079760460 modified "2023-09-25" @default.
- W2079760460 title "Acute and Long-Term Effects of SMS 201-995 in Acromegaly" @default.
- W2079760460 cites W1995079019 @default.
- W2079760460 cites W2006611896 @default.
- W2079760460 cites W2029494927 @default.
- W2079760460 cites W2033434888 @default.
- W2079760460 cites W2060185962 @default.
- W2079760460 cites W2088004056 @default.
- W2079760460 doi "https://doi.org/10.3109/00365528609087442" @default.
- W2079760460 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/2876498" @default.
- W2079760460 hasPublicationYear "1986" @default.
- W2079760460 type Work @default.
- W2079760460 sameAs 2079760460 @default.
- W2079760460 citedByCount "15" @default.
- W2079760460 crossrefType "journal-article" @default.
- W2079760460 hasAuthorship W2079760460A5012841131 @default.
- W2079760460 hasAuthorship W2079760460A5043165222 @default.
- W2079760460 hasConcept C126322002 @default.
- W2079760460 hasConcept C134018914 @default.
- W2079760460 hasConcept C2777433750 @default.
- W2079760460 hasConcept C2778199505 @default.
- W2079760460 hasConcept C2779306644 @default.
- W2079760460 hasConcept C2984496839 @default.
- W2079760460 hasConcept C71315377 @default.
- W2079760460 hasConcept C71924100 @default.
- W2079760460 hasConcept C80862487 @default.
- W2079760460 hasConceptScore W2079760460C126322002 @default.
- W2079760460 hasConceptScore W2079760460C134018914 @default.
- W2079760460 hasConceptScore W2079760460C2777433750 @default.
- W2079760460 hasConceptScore W2079760460C2778199505 @default.
- W2079760460 hasConceptScore W2079760460C2779306644 @default.
- W2079760460 hasConceptScore W2079760460C2984496839 @default.
- W2079760460 hasConceptScore W2079760460C71315377 @default.
- W2079760460 hasConceptScore W2079760460C71924100 @default.
- W2079760460 hasConceptScore W2079760460C80862487 @default.
- W2079760460 hasIssue "sup119" @default.
- W2079760460 hasLocation W20797604601 @default.
- W2079760460 hasLocation W20797604602 @default.
- W2079760460 hasOpenAccess W2079760460 @default.
- W2079760460 hasPrimaryLocation W20797604601 @default.
- W2079760460 hasRelatedWork W2002963912 @default.
- W2079760460 hasRelatedWork W2005525085 @default.
- W2079760460 hasRelatedWork W2022154963 @default.
- W2079760460 hasRelatedWork W2037601963 @default.
- W2079760460 hasRelatedWork W2068807442 @default.
- W2079760460 hasRelatedWork W2072267794 @default.
- W2079760460 hasRelatedWork W2159028105 @default.
- W2079760460 hasRelatedWork W4233275316 @default.
- W2079760460 hasRelatedWork W4247251534 @default.
- W2079760460 hasRelatedWork W2421976456 @default.
- W2079760460 hasVolume "21" @default.
- W2079760460 isParatext "false" @default.
- W2079760460 isRetracted "false" @default.
- W2079760460 magId "2079760460" @default.
- W2079760460 workType "article" @default.