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- W2079774183 abstract "The pathogenesis of pulmonary arterial hypertension (PAH) exhibits many neoplastic‐like features. Cowden syndrome is a difficult‐to‐recognize heritable cancer syndrome caused by a germline mutation in the phosphatase‐and‐tensin homolog deleted on the chromosome 10 ( PTEN ) gene. PTEN regulation has been implicated in cancer development and, more recently, PAH pathogenesis. Here we report a case of PAH in a patient with Cowden syndrome and the response to pulmonary vasodilators." @default.
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- W2079774183 date "2014-12-01" @default.
- W2079774183 modified "2023-10-17" @default.
- W2079774183 title "Pulmonary Arterial Hypertension in a Patient with Cowden Syndrome and the <i>PTEN</i> Mutation" @default.
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- W2079774183 doi "https://doi.org/10.1086/678552" @default.
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