Matches in SemOpenAlex for { <https://semopenalex.org/work/W2079783400> ?p ?o ?g. }
Showing items 1 to 84 of
84
with 100 items per page.
- W2079783400 endingPage "498" @default.
- W2079783400 startingPage "496" @default.
- W2079783400 abstract "The roles of Plasmodium falciparum resistance to chloroquine and compliance in the protective efficacy of the antenatal chloroquine prophylaxis programme in Malawi were evaluated by interviewing pregnant women attending antenatal clinics and examining them for P. falciparum parasites in thick smears and chloroquine metabolites in urine. 36% of 642 women had urine chloroquine metabolite levels compatible with regular compliance to the weekly chloroquine dosage schedule. Among a subgroup of 288 pregnant women who were provided weekly prophylaxis under supervision for 4 consecutive weeks, P. falciparum infection rates were 37%, representing the failure of chloroquine to eliminate P. falciparum in Malawi. Among pregnant women not taking prophylaxis, the P. falciparum infection rate was 48%. Based on the P. falciparum infection rates among these 2 groups of women, the protective efficacy of CQ chloroquine was estimated as 23%. If the 36% of pregnant women who had chloroquine in their urines accurately estimates the proportion of women who comply with the prophylaxis programme in Malawi, the actual protective efficacy of the programme would be 8%. The cost of preventing one P. falciparum infection among pregnant women in the Malawi programme is estimated at US$ 10.87. This is an unacceptably high cost in much of Africa, and research is required to define more cost-effective interventions, including more effective drugs, and health education programmes to improve compliance among pregnant women." @default.
- W2079783400 created "2016-06-24" @default.
- W2079783400 creator A5004642473 @default.
- W2079783400 creator A5019203961 @default.
- W2079783400 creator A5044744240 @default.
- W2079783400 creator A5051553564 @default.
- W2079783400 creator A5068535484 @default.
- W2079783400 creator A5071656227 @default.
- W2079783400 date "1990-07-01" @default.
- W2079783400 modified "2023-09-26" @default.
- W2079783400 title "Antenatal chloroquine chemoprophylaxis in Malawi: chloroquine resistance, compliance, protective efficacy and cost" @default.
- W2079783400 cites W1979995590 @default.
- W2079783400 cites W1991775785 @default.
- W2079783400 cites W2088751208 @default.
- W2079783400 cites W2119667458 @default.
- W2079783400 cites W2410419840 @default.
- W2079783400 cites W74585451 @default.
- W2079783400 doi "https://doi.org/10.1016/0035-9203(90)90011-3" @default.
- W2079783400 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/2091336" @default.
- W2079783400 hasPublicationYear "1990" @default.
- W2079783400 type Work @default.
- W2079783400 sameAs 2079783400 @default.
- W2079783400 citedByCount "52" @default.
- W2079783400 countsByYear W20797834002014 @default.
- W2079783400 countsByYear W20797834002016 @default.
- W2079783400 countsByYear W20797834002017 @default.
- W2079783400 countsByYear W20797834002020 @default.
- W2079783400 crossrefType "journal-article" @default.
- W2079783400 hasAuthorship W2079783400A5004642473 @default.
- W2079783400 hasAuthorship W2079783400A5019203961 @default.
- W2079783400 hasAuthorship W2079783400A5044744240 @default.
- W2079783400 hasAuthorship W2079783400A5051553564 @default.
- W2079783400 hasAuthorship W2079783400A5068535484 @default.
- W2079783400 hasAuthorship W2079783400A5071656227 @default.
- W2079783400 hasConcept C114851261 @default.
- W2079783400 hasConcept C126322002 @default.
- W2079783400 hasConcept C131872663 @default.
- W2079783400 hasConcept C203014093 @default.
- W2079783400 hasConcept C2776688490 @default.
- W2079783400 hasConcept C2777425658 @default.
- W2079783400 hasConcept C2778048844 @default.
- W2079783400 hasConcept C2778371730 @default.
- W2079783400 hasConcept C2779142074 @default.
- W2079783400 hasConcept C2779234561 @default.
- W2079783400 hasConcept C54355233 @default.
- W2079783400 hasConcept C71924100 @default.
- W2079783400 hasConcept C86803240 @default.
- W2079783400 hasConcept C89423630 @default.
- W2079783400 hasConceptScore W2079783400C114851261 @default.
- W2079783400 hasConceptScore W2079783400C126322002 @default.
- W2079783400 hasConceptScore W2079783400C131872663 @default.
- W2079783400 hasConceptScore W2079783400C203014093 @default.
- W2079783400 hasConceptScore W2079783400C2776688490 @default.
- W2079783400 hasConceptScore W2079783400C2777425658 @default.
- W2079783400 hasConceptScore W2079783400C2778048844 @default.
- W2079783400 hasConceptScore W2079783400C2778371730 @default.
- W2079783400 hasConceptScore W2079783400C2779142074 @default.
- W2079783400 hasConceptScore W2079783400C2779234561 @default.
- W2079783400 hasConceptScore W2079783400C54355233 @default.
- W2079783400 hasConceptScore W2079783400C71924100 @default.
- W2079783400 hasConceptScore W2079783400C86803240 @default.
- W2079783400 hasConceptScore W2079783400C89423630 @default.
- W2079783400 hasIssue "4" @default.
- W2079783400 hasLocation W20797834001 @default.
- W2079783400 hasLocation W20797834002 @default.
- W2079783400 hasOpenAccess W2079783400 @default.
- W2079783400 hasPrimaryLocation W20797834001 @default.
- W2079783400 hasRelatedWork W1974383137 @default.
- W2079783400 hasRelatedWork W1985987993 @default.
- W2079783400 hasRelatedWork W2011160955 @default.
- W2079783400 hasRelatedWork W2059543740 @default.
- W2079783400 hasRelatedWork W2145413350 @default.
- W2079783400 hasRelatedWork W2156134301 @default.
- W2079783400 hasRelatedWork W2410664658 @default.
- W2079783400 hasRelatedWork W2500304171 @default.
- W2079783400 hasRelatedWork W4244592364 @default.
- W2079783400 hasRelatedWork W4300182449 @default.
- W2079783400 hasVolume "84" @default.
- W2079783400 isParatext "false" @default.
- W2079783400 isRetracted "false" @default.
- W2079783400 magId "2079783400" @default.
- W2079783400 workType "article" @default.