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- W2079784583 abstract "<h3>Summary points</h3> Bone marrow transplantation is becoming an increasingly used medical intervention Allogeneic bone marrow transplantation remains a risky medicalprocedure, with mortality about 30%, primarily from graft versus hostdisease and infection; autologous trans- plantation has a more acceptable mortality risk of 5–10% If results of ongoing trials in solid tumours are favourable autologous bone marrow trans- plantation may become a very common form of medical treatment Stem cells collected from peripheral blood are increasingly being used in place of conventional autologous transplantation; they lead to more rapid engraftment, reduce duration of hospitalisation, and may help to control costs As patient numbers increase, general practi- tioners will increasingly be confronted with the long term complications of bone marrow trans- plantation, such as infertility, secondary neo- plasms, and endocrine dysfunction Although most survivors of bone marrow transplantation do well after transplant, 25–50% of patients will have sexual, employment, and psychosocial problems" @default.
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- W2079784583 title "Fortnightly Review: Bone marrow transplantation" @default.
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- W2079784583 doi "https://doi.org/10.1136/bmj.310.6971.31" @default.
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