FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2079807536> ?p ?o ?g. }

• W2079807536 endingPage "504" @default.
• W2079807536 startingPage "499" @default.
• W2079807536 abstract "Tissue viability imaging (TIVI) is a novel polarization spectroscopy method for assessing dermal vascular viability. The purpose of the present study was to compare TIVI with laser Doppler flowmetry (LDF) for assessment of pharmacologically induced vasodilation and vasoconstriction in human skin. Eight individual skin sites on the backs of seven healthy volunteers were randomized to receive an intradermal injection of prostaglandin E2 (PGE2, 10− 6 to 10− 9 M), norepinephrine (NE, 10− 5 to 10− 7 M), or vehicle. Vascular responses were measured by TIVI and LDF at the injection sites at 1-min intervals starting 2 min before and ending 15 min after the skin challenge. TIVI and LDF demonstrated significant dose-dependent and time-related vasodilator responses to PGE2 and vasoconstrictor responses to NE, respectively (p < 0.001). The time course and dose–response functions for LDF and TIVI showed notable differences. Dose–response data showed a significant reduction in TIVI signal with NE 10-7 M (10− 6 NE with LDF) whereas PGE2 10− 6 M was required to elicit a significant increase in TIVI signal (10− 8 M PGE2 with LDF). TIVI demonstrated relative vascular response changes of 0.79 to 1.63 of baseline values at 15 min with NE 10− 5 M or PGE2 10− 6 M compared to values of 0.59 to 8.38 with LDF. There was a modest though significant correlation between relative changes in vascular responses measured by the two methods (p < 0.0001, r2 = 0.521). A Bland–Altman difference plot demonstrated significant underestimation of relative increase versus baseline measured by TIVI (r2 = 0.99, p < 0.0001). We conclude that TIVI polarization spectroscopy is a sensitive method for measurement of NE-induced vascular responses but that it is less sensitive than LDF for measurement of the PGE2-induced reactions." @default.
• W2079807536 created "2016-06-24" @default.
• W2079807536 creator A5051346531 @default.
• W2079807536 creator A5057819012 @default.
• W2079807536 creator A5078339011 @default.
• W2079807536 creator A5079405757 @default.
• W2079807536 date "2010-12-01" @default.
• W2079807536 modified "2023-10-03" @default.
• W2079807536 title "Tissue viability imaging for assessment of pharmacologically induced vasodilation and vasoconstriction in human skin" @default.
• W2079807536 cites W1968775361 @default.
• W2079807536 cites W1968898826 @default.
• W2079807536 cites W1972810592 @default.
• W2079807536 cites W1989334428 @default.
• W2079807536 cites W1997645648 @default.
• W2079807536 cites W1997716961 @default.
• W2079807536 cites W2012488901 @default.
• W2079807536 cites W2013475685 @default.
• W2079807536 cites W2018260600 @default.
• W2079807536 cites W2020421044 @default.
• W2079807536 cites W2020957243 @default.
• W2079807536 cites W2025411917 @default.
• W2079807536 cites W2025539014 @default.
• W2079807536 cites W2031466036 @default.
• W2079807536 cites W2034452985 @default.
• W2079807536 cites W2036892101 @default.
• W2079807536 cites W2047428299 @default.
• W2079807536 cites W2047760067 @default.
• W2079807536 cites W2048526317 @default.
• W2079807536 cites W2052199593 @default.
• W2079807536 cites W2058877400 @default.
• W2079807536 cites W2068884151 @default.
• W2079807536 cites W2080842941 @default.
• W2079807536 cites W2083609417 @default.
• W2079807536 cites W2089045325 @default.
• W2079807536 cites W2094873648 @default.
• W2079807536 cites W2114839748 @default.
• W2079807536 doi "https://doi.org/10.1016/j.mvr.2010.07.011" @default.
• W2079807536 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/20691707" @default.
• W2079807536 hasPublicationYear "2010" @default.
• W2079807536 type Work @default.
• W2079807536 sameAs 2079807536 @default.
• W2079807536 citedByCount "13" @default.
• W2079807536 countsByYear W20798075362013 @default.
• W2079807536 countsByYear W20798075362014 @default.
• W2079807536 countsByYear W20798075362015 @default.
• W2079807536 countsByYear W20798075362016 @default.
• W2079807536 countsByYear W20798075362019 @default.
• W2079807536 countsByYear W20798075362020 @default.
• W2079807536 crossrefType "journal-article" @default.
• W2079807536 hasAuthorship W2079807536A5051346531 @default.
• W2079807536 hasAuthorship W2079807536A5057819012 @default.
• W2079807536 hasAuthorship W2079807536A5078339011 @default.
• W2079807536 hasAuthorship W2079807536A5079405757 @default.
• W2079807536 hasConcept C120770815 @default.
• W2079807536 hasConcept C126322002 @default.
• W2079807536 hasConcept C12722491 @default.
• W2079807536 hasConcept C158846371 @default.
• W2079807536 hasConcept C2779961880 @default.
• W2079807536 hasConcept C2908519926 @default.
• W2079807536 hasConcept C42219234 @default.
• W2079807536 hasConcept C52305850 @default.
• W2079807536 hasConcept C71924100 @default.
• W2079807536 hasConceptScore W2079807536C120770815 @default.
• W2079807536 hasConceptScore W2079807536C126322002 @default.
• W2079807536 hasConceptScore W2079807536C12722491 @default.
• W2079807536 hasConceptScore W2079807536C158846371 @default.
• W2079807536 hasConceptScore W2079807536C2779961880 @default.
• W2079807536 hasConceptScore W2079807536C2908519926 @default.
• W2079807536 hasConceptScore W2079807536C42219234 @default.
• W2079807536 hasConceptScore W2079807536C52305850 @default.
• W2079807536 hasConceptScore W2079807536C71924100 @default.
• W2079807536 hasIssue "3" @default.
• W2079807536 hasLocation W20798075361 @default.
• W2079807536 hasLocation W20798075362 @default.
• W2079807536 hasOpenAccess W2079807536 @default.
• W2079807536 hasPrimaryLocation W20798075361 @default.
• W2079807536 hasRelatedWork W1483721997 @default.
• W2079807536 hasRelatedWork W1521960142 @default.
• W2079807536 hasRelatedWork W1963692787 @default.
• W2079807536 hasRelatedWork W1969527081 @default.
• W2079807536 hasRelatedWork W2025411917 @default.
• W2079807536 hasRelatedWork W2037815595 @default.
• W2079807536 hasRelatedWork W2079807536 @default.
• W2079807536 hasRelatedWork W2095371362 @default.
• W2079807536 hasRelatedWork W2125386883 @default.
• W2079807536 hasRelatedWork W600848024 @default.
• W2079807536 hasVolume "80" @default.
• W2079807536 isParatext "false" @default.
• W2079807536 isRetracted "false" @default.
• W2079807536 magId "2079807536" @default.
• W2079807536 workType "article" @default.