Matches in SemOpenAlex for { <https://semopenalex.org/work/W2079809295> ?p ?o ?g. }
Showing items 1 to 99 of
99
with 100 items per page.
- W2079809295 endingPage "3033" @default.
- W2079809295 startingPage "3028" @default.
- W2079809295 abstract "The effects of ionic strength, pH, and temperature on three separate aspects of prothrombin-phospholipid membrane binding were studied. The three parameters include a calcium-dependent protein transition, a calcium-membrane interation, and, finally, the binding of calcium-saturated protein to a calcium-saturated phospholipid membrane. The results are consistent with calcium binding to carbonyl groups in the protein and to phosphate in the phospholipids. These interactions show the expected pH profiles and sensitivity to ionic strength. Temperature effects indicate a small negative enthalpy change for each process. The binding of calcium-saturated protein to calcium-saturated membrane shows very little variation between pH 6 and pH 9, is accompanied by no detected enthalpy change, and is relatively insensitive to ionic strength. These latter results indicate that ionic calcium bridging between the protein and membrane is not important. A chelation model for prothrombin-membrane binding is proposed where the two interacting species have no net charge; ligands on the protein complete the coordination sphere of membrane-bound calcium and vice versa." @default.
- W2079809295 created "2016-06-24" @default.
- W2079809295 creator A5023957817 @default.
- W2079809295 creator A5029681264 @default.
- W2079809295 date "1980-06-24" @default.
- W2079809295 modified "2023-09-26" @default.
- W2079809295 title "Prothrombin-membrane interaction. Effects of ionic strength, pH, and temperature" @default.
- W2079809295 cites W1527880353 @default.
- W2079809295 cites W1595472253 @default.
- W2079809295 cites W1598353420 @default.
- W2079809295 cites W1603919509 @default.
- W2079809295 cites W181379507 @default.
- W2079809295 cites W1976319018 @default.
- W2079809295 cites W1985111499 @default.
- W2079809295 cites W1985342306 @default.
- W2079809295 cites W2005725134 @default.
- W2079809295 cites W2006764976 @default.
- W2079809295 cites W2022710224 @default.
- W2079809295 cites W2027203230 @default.
- W2079809295 cites W2059996478 @default.
- W2079809295 cites W2065156100 @default.
- W2079809295 cites W2069051033 @default.
- W2079809295 cites W2069164250 @default.
- W2079809295 cites W2073402311 @default.
- W2079809295 cites W2074567743 @default.
- W2079809295 cites W2076932299 @default.
- W2079809295 cites W2093397934 @default.
- W2079809295 cites W2096326108 @default.
- W2079809295 cites W2156393985 @default.
- W2079809295 cites W2253374107 @default.
- W2079809295 cites W2408833597 @default.
- W2079809295 cites W296710421 @default.
- W2079809295 cites W98911413 @default.
- W2079809295 doi "https://doi.org/10.1021/bi00554a030" @default.
- W2079809295 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/7397115" @default.
- W2079809295 hasPublicationYear "1980" @default.
- W2079809295 type Work @default.
- W2079809295 sameAs 2079809295 @default.
- W2079809295 citedByCount "33" @default.
- W2079809295 countsByYear W20798092952015 @default.
- W2079809295 crossrefType "journal-article" @default.
- W2079809295 hasAuthorship W2079809295A5023957817 @default.
- W2079809295 hasAuthorship W2079809295A5029681264 @default.
- W2079809295 hasConcept C121332964 @default.
- W2079809295 hasConcept C12554922 @default.
- W2079809295 hasConcept C145148216 @default.
- W2079809295 hasConcept C178790620 @default.
- W2079809295 hasConcept C179104552 @default.
- W2079809295 hasConcept C184651966 @default.
- W2079809295 hasConcept C185592680 @default.
- W2079809295 hasConcept C187428577 @default.
- W2079809295 hasConcept C2182769 @default.
- W2079809295 hasConcept C2778918659 @default.
- W2079809295 hasConcept C3288061 @default.
- W2079809295 hasConcept C41625074 @default.
- W2079809295 hasConcept C519063684 @default.
- W2079809295 hasConcept C55493867 @default.
- W2079809295 hasConcept C8010536 @default.
- W2079809295 hasConcept C86803240 @default.
- W2079809295 hasConcept C97355855 @default.
- W2079809295 hasConceptScore W2079809295C121332964 @default.
- W2079809295 hasConceptScore W2079809295C12554922 @default.
- W2079809295 hasConceptScore W2079809295C145148216 @default.
- W2079809295 hasConceptScore W2079809295C178790620 @default.
- W2079809295 hasConceptScore W2079809295C179104552 @default.
- W2079809295 hasConceptScore W2079809295C184651966 @default.
- W2079809295 hasConceptScore W2079809295C185592680 @default.
- W2079809295 hasConceptScore W2079809295C187428577 @default.
- W2079809295 hasConceptScore W2079809295C2182769 @default.
- W2079809295 hasConceptScore W2079809295C2778918659 @default.
- W2079809295 hasConceptScore W2079809295C3288061 @default.
- W2079809295 hasConceptScore W2079809295C41625074 @default.
- W2079809295 hasConceptScore W2079809295C519063684 @default.
- W2079809295 hasConceptScore W2079809295C55493867 @default.
- W2079809295 hasConceptScore W2079809295C8010536 @default.
- W2079809295 hasConceptScore W2079809295C86803240 @default.
- W2079809295 hasConceptScore W2079809295C97355855 @default.
- W2079809295 hasIssue "13" @default.
- W2079809295 hasLocation W20798092951 @default.
- W2079809295 hasLocation W20798092952 @default.
- W2079809295 hasOpenAccess W2079809295 @default.
- W2079809295 hasPrimaryLocation W20798092951 @default.
- W2079809295 hasRelatedWork W1599335243 @default.
- W2079809295 hasRelatedWork W1866194841 @default.
- W2079809295 hasRelatedWork W2023985738 @default.
- W2079809295 hasRelatedWork W2057689062 @default.
- W2079809295 hasRelatedWork W2070228259 @default.
- W2079809295 hasRelatedWork W2071565677 @default.
- W2079809295 hasRelatedWork W2071965538 @default.
- W2079809295 hasRelatedWork W2092360065 @default.
- W2079809295 hasRelatedWork W2140922644 @default.
- W2079809295 hasRelatedWork W2415712585 @default.
- W2079809295 hasVolume "19" @default.
- W2079809295 isParatext "false" @default.
- W2079809295 isRetracted "false" @default.
- W2079809295 magId "2079809295" @default.
- W2079809295 workType "article" @default.