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- W2079824715 abstract "Decades ago, we and others proposed that the dynamic interplay between a cell and its surrounding environment dictates cell phenotype and tissue structure. Whereas much has been discovered about the effects of extracellular matrix molecules on cell growth and tissue-specific gene expression, the nuclear mechanisms through which these molecules promote these physiological events remain unknown. Using mammary epithelial cells as a model, the purpose of this review is to discuss how the extracellular matrix influences nuclear structure and function in a three-dimensional context to promote epithelial morphogenesis and function in the mammary gland." @default.
- W2079824715 created "2016-06-24" @default.
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- W2079824715 date "2010-01-28" @default.
- W2079824715 modified "2023-09-23" @default.
- W2079824715 title "Gene Expression in the Third Dimension: The ECM-nucleus Connection" @default.
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- W2079824715 doi "https://doi.org/10.1007/s10911-010-9163-3" @default.
- W2079824715 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/2912292" @default.
- W2079824715 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/20107877" @default.
- W2079824715 hasPublicationYear "2010" @default.
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