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• W2079838454 abstract "Memory awareness in early Alzheimer’s disease (AD) influences capacity to provide informed consent for a memory treatment. This study investigated the extent to which aspects of memory awareness influence everyday decision-making capacity about medication management in AD. 42 participants with mild AD and 50 healthy elders underwent clinical ratings of memory awareness, metamemory testing, and an interview of everyday decision-making capacity regarding medication management. 45% of AD subjects were classified as aware (AAD) and 55% as unaware (UAD) based on clinical ratings and supported by metamemory testing (<mml:math xmlns:mml=http://www.w3.org/1998/Math/MathML><mml:mi>P</mml:mi><mml:mo>=</mml:mo><mml:mn>.015</mml:mn></mml:math>). Capacity was impaired in each of the AD groups as compared to the healthy elders<mml:math xmlns:mml=http://www.w3.org/1998/Math/MathML><mml:mi>F</mml:mi><mml:mn>(2, 67)</mml:mn><mml:mo>=</mml:mo><mml:mn>17.63</mml:mn></mml:math>, UAD,<mml:math xmlns:mml=http://www.w3.org/1998/Math/MathML><mml:mi>P</mml:mi><mml:mo><</mml:mo><mml:mn>.01</mml:mn></mml:math>; AAD,<mml:math xmlns:mml=http://www.w3.org/1998/Math/MathML><mml:mi>P</mml:mi><mml:mo>=</mml:mo><mml:mn>.01</mml:mn></mml:math>). Within the AD group, capacity correlated selectively with awareness as measured with clinical ratings (<mml:math xmlns:mml=http://www.w3.org/1998/Math/MathML><mml:mi>r</mml:mi><mml:mo>=</mml:mo><mml:mn>−.41</mml:mn></mml:math>,<mml:math xmlns:mml=http://www.w3.org/1998/Math/MathML><mml:mi>P</mml:mi><mml:mo>=</mml:mo><mml:mn>.007</mml:mn></mml:math>) but not objective metamemory testing (<mml:math xmlns:mml=http://www.w3.org/1998/Math/MathML><mml:mi>r</mml:mi><mml:mo>=</mml:mo><mml:mn>−.10</mml:mn></mml:math>,<mml:math xmlns:mml=http://www.w3.org/1998/Math/MathML><mml:mi>P</mml:mi><mml:mo>=</mml:mo><mml:mn>.60</mml:mn></mml:math>). Appreciation scores were lower in UAD as compared with AAD<mml:math xmlns:mml=http://www.w3.org/1998/Math/MathML><mml:mi>F</mml:mi><mml:mo>(1, 35)</mml:mo><mml:mo>=</mml:mo><mml:mn>8.36</mml:mn></mml:math>,<mml:math xmlns:mml=http://www.w3.org/1998/Math/MathML><mml:mi>P</mml:mi><mml:mo>=</mml:mo><mml:mn>.007</mml:mn></mml:math>. Unawareness of memory loss should heighten clinicians’ concern about everyday decision-making capacity in AD." @default.
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• W2079838454 date "2011-01-01" @default.
• W2079838454 modified "2023-10-16" @default.
• W2079838454 title "Memory Awareness Influences Everyday Decision Making Capacity about Medication Management in Alzheimer's Disease" @default.
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• W2079838454 doi "https://doi.org/10.4061/2011/483897" @default.
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