FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2079841346> ?p ?o ?g. }

• W2079841346 endingPage "228" @default.
• W2079841346 startingPage "224" @default.
• W2079841346 abstract "In order to investigate the associations of SCNN1A, SCNN1G and SCNN1B genes with blood pressure (BP) in the Han Chinese population, we included 2880 participants did not use antihypertensive medication in the month prior to the baseline survey in the current analysis. Forty-four tag-single-nucleotide polymorphisms (SNPs) in epithelial sodium channel (ENaC) genes were selected and genotyped, and nine BP measurements were obtained during the 3-day examination. In the single-marker analyses, we identified significant associations of SCNN1A marker rs13306613 with diastolic BP (DBP) and SCNN1B marker rs12447134 with systolic BP (SBP) under codominant model after Bonferroni’s correction (P=2.82 × 10−5 and 4.63 × 10−4, respectively). In addition, five SNPs in SCNN1G and four SNPs in SCNN1B achieved nominal significance for SBP, DBP or mean arterial pressure (MAP) under the additive model. For example, the minor C allele of rs5735 in SCNN1G gene was associated with decreased SBP, DBP and MAP (P=0.016, 5.41 × 10−3 and 4.36 × 10−3, respectively). Gene-based results showed significant associations of SCNN1G and SCNN1B with BP levels. This study suggested that ENaC genes have important roles in BP regulation in the Han Chinese population. Future studies are warranted to replicate these findings, and functional studies are needed to identify true causal variants in ENaC genes." @default.
• W2079841346 created "2016-06-24" @default.
• W2079841346 creator A5005459063 @default.
• W2079841346 creator A5010066091 @default.
• W2079841346 creator A5014621167 @default.
• W2079841346 creator A5025557155 @default.
• W2079841346 creator A5038404711 @default.
• W2079841346 creator A5040051974 @default.
• W2079841346 creator A5052883326 @default.
• W2079841346 creator A5054280155 @default.
• W2079841346 creator A5059979152 @default.
• W2079841346 creator A5065423973 @default.
• W2079841346 creator A5067586446 @default.
• W2079841346 creator A5077871646 @default.
• W2079841346 creator A5079235161 @default.
• W2079841346 creator A5080338655 @default.
• W2079841346 creator A5086557925 @default.
• W2079841346 creator A5089476625 @default.
• W2079841346 date "2014-09-18" @default.
• W2079841346 modified "2023-09-26" @default.
• W2079841346 title "Associations of epithelial sodium channel genes with blood pressure: the GenSalt study" @default.
• W2079841346 cites W1512508196 @default.
• W2079841346 cites W1963700991 @default.
• W2079841346 cites W2002044934 @default.
• W2079841346 cites W2007362372 @default.
• W2079841346 cites W2015170358 @default.
• W2079841346 cites W2020695341 @default.
• W2079841346 cites W2031190713 @default.
• W2079841346 cites W2042127480 @default.
• W2079841346 cites W2043790702 @default.
• W2079841346 cites W2061583392 @default.
• W2079841346 cites W2071206094 @default.
• W2079841346 cites W2076279261 @default.
• W2079841346 cites W2077532457 @default.
• W2079841346 cites W2083914594 @default.
• W2079841346 cites W2088248574 @default.
• W2079841346 cites W2098347923 @default.
• W2079841346 cites W2110689704 @default.
• W2079841346 cites W2115593328 @default.
• W2079841346 cites W2119979251 @default.
• W2079841346 cites W2124663880 @default.
• W2079841346 cites W2124699736 @default.
• W2079841346 cites W2127334295 @default.
• W2079841346 cites W2127950980 @default.
• W2079841346 cites W2144360877 @default.
• W2079841346 cites W2157359283 @default.
• W2079841346 cites W2159392143 @default.
• W2079841346 cites W2161633633 @default.
• W2079841346 cites W2162530578 @default.
• W2079841346 cites W2168158644 @default.
• W2079841346 cites W2169213514 @default.
• W2079841346 cites W2171813412 @default.
• W2079841346 cites W2331782418 @default.
• W2079841346 cites W4248519369 @default.
• W2079841346 cites W4254209755 @default.
• W2079841346 doi "https://doi.org/10.1038/jhh.2014.78" @default.
• W2079841346 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/4357546" @default.
• W2079841346 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/25231509" @default.
• W2079841346 hasPublicationYear "2014" @default.
• W2079841346 type Work @default.
• W2079841346 sameAs 2079841346 @default.
• W2079841346 citedByCount "9" @default.
• W2079841346 countsByYear W20798413462016 @default.
• W2079841346 countsByYear W20798413462018 @default.
• W2079841346 countsByYear W20798413462019 @default.
• W2079841346 countsByYear W20798413462020 @default.
• W2079841346 countsByYear W20798413462021 @default.
• W2079841346 countsByYear W20798413462022 @default.
• W2079841346 countsByYear W20798413462023 @default.
• W2079841346 crossrefType "journal-article" @default.
• W2079841346 hasAuthorship W2079841346A5005459063 @default.
• W2079841346 hasAuthorship W2079841346A5010066091 @default.
• W2079841346 hasAuthorship W2079841346A5014621167 @default.
• W2079841346 hasAuthorship W2079841346A5025557155 @default.
• W2079841346 hasAuthorship W2079841346A5038404711 @default.
• W2079841346 hasAuthorship W2079841346A5040051974 @default.
• W2079841346 hasAuthorship W2079841346A5052883326 @default.
• W2079841346 hasAuthorship W2079841346A5054280155 @default.
• W2079841346 hasAuthorship W2079841346A5059979152 @default.
• W2079841346 hasAuthorship W2079841346A5065423973 @default.
• W2079841346 hasAuthorship W2079841346A5067586446 @default.
• W2079841346 hasAuthorship W2079841346A5077871646 @default.
• W2079841346 hasAuthorship W2079841346A5079235161 @default.
• W2079841346 hasAuthorship W2079841346A5080338655 @default.
• W2079841346 hasAuthorship W2079841346A5086557925 @default.
• W2079841346 hasAuthorship W2079841346A5089476625 @default.
• W2079841346 hasBestOaLocation W20798413461 @default.
• W2079841346 hasConcept C104317684 @default.
• W2079841346 hasConcept C105795698 @default.
• W2079841346 hasConcept C126322002 @default.
• W2079841346 hasConcept C127808970 @default.
• W2079841346 hasConcept C135763542 @default.
• W2079841346 hasConcept C153209595 @default.
• W2079841346 hasConcept C178790620 @default.
• W2079841346 hasConcept C180754005 @default.
• W2079841346 hasConcept C185592680 @default.
• W2079841346 hasConcept C2908647359 @default.
• W2079841346 hasConcept C33923547 @default.

• next