Matches in SemOpenAlex for { <https://semopenalex.org/work/W2079863610> ?p ?o ?g. }
Showing items 1 to 75 of
75
with 100 items per page.
- W2079863610 endingPage "62" @default.
- W2079863610 startingPage "62" @default.
- W2079863610 abstract "In the course of examining the actions of the cholecystokinin octapeptide (CCK-8) on pancreatic acini we found that CCK-8 can stimulate release of the large-molecular-weight cytoplasmic protein, lactate dehydrogenase (LDH) by as much as 6-fold. CCK-8-stimulated LDH release is mediated by a CCK-preferring receptor, detectable at 100 pM CCK-8, maximal at 100 nM CCK-8, constant for up to 30 min, reversible, not desensitized, and dependent on oxidative metabolism and incubation temperature but not on calcium in the extracellular medium. This action of CCK-8 is blocked by inhibitors of protein kinases, staurosporine, H-7, H-8 and H-9, but not by calmodulin antagonists, chlorpromazine, trifluoperazine or W-7. This action of CCK-8 on LDH release is not reproduced by TPA, 8Br-cAMP or A23187. Thus, it appears to be mediated by a previously uncharacterized protein kinase or an isoform of protein kinase C that is not maximally stimulated by TPA." @default.
- W2079863610 created "2016-06-24" @default.
- W2079863610 creator A5067182728 @default.
- W2079863610 date "1993-09-01" @default.
- W2079863610 modified "2023-10-16" @default.
- W2079863610 title "Variability and expression of the human factor H gene family" @default.
- W2079863610 doi "https://doi.org/10.1016/0161-5890(93)90408-4" @default.
- W2079863610 hasPublicationYear "1993" @default.
- W2079863610 type Work @default.
- W2079863610 sameAs 2079863610 @default.
- W2079863610 citedByCount "0" @default.
- W2079863610 crossrefType "journal-article" @default.
- W2079863610 hasAuthorship W2079863610A5067182728 @default.
- W2079863610 hasConcept C104317684 @default.
- W2079863610 hasConcept C126322002 @default.
- W2079863610 hasConcept C134018914 @default.
- W2079863610 hasConcept C153911025 @default.
- W2079863610 hasConcept C170493617 @default.
- W2079863610 hasConcept C181199279 @default.
- W2079863610 hasConcept C184235292 @default.
- W2079863610 hasConcept C185592680 @default.
- W2079863610 hasConcept C25642318 @default.
- W2079863610 hasConcept C2775891158 @default.
- W2079863610 hasConcept C2777593968 @default.
- W2079863610 hasConcept C2779084600 @default.
- W2079863610 hasConcept C28406088 @default.
- W2079863610 hasConcept C29688787 @default.
- W2079863610 hasConcept C32110497 @default.
- W2079863610 hasConcept C519063684 @default.
- W2079863610 hasConcept C53345823 @default.
- W2079863610 hasConcept C55493867 @default.
- W2079863610 hasConcept C71924100 @default.
- W2079863610 hasConcept C86803240 @default.
- W2079863610 hasConcept C97029542 @default.
- W2079863610 hasConceptScore W2079863610C104317684 @default.
- W2079863610 hasConceptScore W2079863610C126322002 @default.
- W2079863610 hasConceptScore W2079863610C134018914 @default.
- W2079863610 hasConceptScore W2079863610C153911025 @default.
- W2079863610 hasConceptScore W2079863610C170493617 @default.
- W2079863610 hasConceptScore W2079863610C181199279 @default.
- W2079863610 hasConceptScore W2079863610C184235292 @default.
- W2079863610 hasConceptScore W2079863610C185592680 @default.
- W2079863610 hasConceptScore W2079863610C25642318 @default.
- W2079863610 hasConceptScore W2079863610C2775891158 @default.
- W2079863610 hasConceptScore W2079863610C2777593968 @default.
- W2079863610 hasConceptScore W2079863610C2779084600 @default.
- W2079863610 hasConceptScore W2079863610C28406088 @default.
- W2079863610 hasConceptScore W2079863610C29688787 @default.
- W2079863610 hasConceptScore W2079863610C32110497 @default.
- W2079863610 hasConceptScore W2079863610C519063684 @default.
- W2079863610 hasConceptScore W2079863610C53345823 @default.
- W2079863610 hasConceptScore W2079863610C55493867 @default.
- W2079863610 hasConceptScore W2079863610C71924100 @default.
- W2079863610 hasConceptScore W2079863610C86803240 @default.
- W2079863610 hasConceptScore W2079863610C97029542 @default.
- W2079863610 hasLocation W20798636101 @default.
- W2079863610 hasOpenAccess W2079863610 @default.
- W2079863610 hasPrimaryLocation W20798636101 @default.
- W2079863610 hasRelatedWork W1977702912 @default.
- W2079863610 hasRelatedWork W1982594208 @default.
- W2079863610 hasRelatedWork W2031272904 @default.
- W2079863610 hasRelatedWork W2034906614 @default.
- W2079863610 hasRelatedWork W2042209138 @default.
- W2079863610 hasRelatedWork W2048534045 @default.
- W2079863610 hasRelatedWork W2063662253 @default.
- W2079863610 hasRelatedWork W2069633620 @default.
- W2079863610 hasRelatedWork W4238501047 @default.
- W2079863610 hasRelatedWork W2043830906 @default.
- W2079863610 hasVolume "30" @default.
- W2079863610 isParatext "false" @default.
- W2079863610 isRetracted "false" @default.
- W2079863610 magId "2079863610" @default.
- W2079863610 workType "article" @default.