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- W2079880079 abstract "Immune evasion is recognized as a key strategy for cancer survival and progression. With increased understanding of immune escape mechanisms, the development of immunotherapies to restore anti-tumor immune responses has flourished. Immuno-oncology (I-O) agents targeting checkpoints in the immune regulation cascade currently form the mainstay of approaches of cancer immunotherapy. Since initial success in melanoma, evidence for the notable effects of the I-O modality has been expanding, with numerous clinical studies underway or completed in a variety of solid tumors, including non-small cell lung cancer. This review highlights the rationale and potential role of immunotherapy in non-small cell lung cancer management, with a focus on immune checkpoint inhibitors. We also discuss the potential for I-O-based combination therapy." @default.
- W2079880079 created "2016-06-24" @default.
- W2079880079 creator A5046728958 @default.
- W2079880079 creator A5061972659 @default.
- W2079880079 date "2014-09-09" @default.
- W2079880079 modified "2023-09-24" @default.
- W2079880079 title "Exploring the potential of immuno-oncology-based treatment for patients with non-small cell lung cancer" @default.
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- W2079880079 doi "https://doi.org/10.1586/14737140.2015.957187" @default.
- W2079880079 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/25199617" @default.
- W2079880079 hasPublicationYear "2014" @default.
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