Matches in SemOpenAlex for { <https://semopenalex.org/work/W2079888510> ?p ?o ?g. }
Showing items 1 to 94 of
94
with 100 items per page.
- W2079888510 endingPage "1463" @default.
- W2079888510 startingPage "1459" @default.
- W2079888510 abstract "A new class of melanocortin 4 receptor (MC4r) agonists was discovered from an unexpected sidereaction in which formaldehyde caused cyclization. These cyclophanes were found to be sub micromolar agonists of the MC1 and MC4 and were less potent on the MC3 and MC5 receptor. They were shown to compete with the peptidic antagonist SHU9119 for binding to the MC4 receptor. In an acute feeding study in Sprague Dawley rats, food intake was reduced more than 50% versus vehicle after 3 h at a dose of 1 mg/kg." @default.
- W2079888510 created "2016-06-24" @default.
- W2079888510 creator A5026982180 @default.
- W2079888510 creator A5042753052 @default.
- W2079888510 creator A5064830959 @default.
- W2079888510 creator A5064954760 @default.
- W2079888510 creator A5071261730 @default.
- W2079888510 creator A5079273451 @default.
- W2079888510 creator A5081615839 @default.
- W2079888510 date "2011-03-01" @default.
- W2079888510 modified "2023-10-17" @default.
- W2079888510 title "Serendipitous discovery of a new class of agonists for the melanocortin 1 and 4 receptors and a new class of cyclophanes" @default.
- W2079888510 cites W1597982565 @default.
- W2079888510 cites W1974256272 @default.
- W2079888510 cites W1979382449 @default.
- W2079888510 cites W1989904048 @default.
- W2079888510 cites W1993544190 @default.
- W2079888510 cites W2015370922 @default.
- W2079888510 cites W2016445827 @default.
- W2079888510 cites W2018085228 @default.
- W2079888510 cites W2024895193 @default.
- W2079888510 cites W2050442066 @default.
- W2079888510 cites W2068996270 @default.
- W2079888510 cites W2086722805 @default.
- W2079888510 cites W2105470099 @default.
- W2079888510 cites W2116058026 @default.
- W2079888510 cites W2155119858 @default.
- W2079888510 cites W2184401029 @default.
- W2079888510 cites W337246211 @default.
- W2079888510 cites W4250023941 @default.
- W2079888510 doi "https://doi.org/10.1016/j.bmcl.2011.01.011" @default.
- W2079888510 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/21277204" @default.
- W2079888510 hasPublicationYear "2011" @default.
- W2079888510 type Work @default.
- W2079888510 sameAs 2079888510 @default.
- W2079888510 citedByCount "6" @default.
- W2079888510 countsByYear W20798885102012 @default.
- W2079888510 countsByYear W20798885102013 @default.
- W2079888510 countsByYear W20798885102017 @default.
- W2079888510 countsByYear W20798885102021 @default.
- W2079888510 crossrefType "journal-article" @default.
- W2079888510 hasAuthorship W2079888510A5026982180 @default.
- W2079888510 hasAuthorship W2079888510A5042753052 @default.
- W2079888510 hasAuthorship W2079888510A5064830959 @default.
- W2079888510 hasAuthorship W2079888510A5064954760 @default.
- W2079888510 hasAuthorship W2079888510A5071261730 @default.
- W2079888510 hasAuthorship W2079888510A5079273451 @default.
- W2079888510 hasAuthorship W2079888510A5081615839 @default.
- W2079888510 hasConcept C126322002 @default.
- W2079888510 hasConcept C134018914 @default.
- W2079888510 hasConcept C170493617 @default.
- W2079888510 hasConcept C185592680 @default.
- W2079888510 hasConcept C2776885963 @default.
- W2079888510 hasConcept C2777241137 @default.
- W2079888510 hasConcept C2778938600 @default.
- W2079888510 hasConcept C2779993316 @default.
- W2079888510 hasConcept C43295716 @default.
- W2079888510 hasConcept C55493867 @default.
- W2079888510 hasConcept C71240020 @default.
- W2079888510 hasConcept C71924100 @default.
- W2079888510 hasConceptScore W2079888510C126322002 @default.
- W2079888510 hasConceptScore W2079888510C134018914 @default.
- W2079888510 hasConceptScore W2079888510C170493617 @default.
- W2079888510 hasConceptScore W2079888510C185592680 @default.
- W2079888510 hasConceptScore W2079888510C2776885963 @default.
- W2079888510 hasConceptScore W2079888510C2777241137 @default.
- W2079888510 hasConceptScore W2079888510C2778938600 @default.
- W2079888510 hasConceptScore W2079888510C2779993316 @default.
- W2079888510 hasConceptScore W2079888510C43295716 @default.
- W2079888510 hasConceptScore W2079888510C55493867 @default.
- W2079888510 hasConceptScore W2079888510C71240020 @default.
- W2079888510 hasConceptScore W2079888510C71924100 @default.
- W2079888510 hasIssue "5" @default.
- W2079888510 hasLocation W20798885101 @default.
- W2079888510 hasLocation W20798885102 @default.
- W2079888510 hasOpenAccess W2079888510 @default.
- W2079888510 hasPrimaryLocation W20798885101 @default.
- W2079888510 hasRelatedWork W1987986705 @default.
- W2079888510 hasRelatedWork W1997028667 @default.
- W2079888510 hasRelatedWork W1998321044 @default.
- W2079888510 hasRelatedWork W2026232155 @default.
- W2079888510 hasRelatedWork W2026885176 @default.
- W2079888510 hasRelatedWork W2039353044 @default.
- W2079888510 hasRelatedWork W2065987916 @default.
- W2079888510 hasRelatedWork W2080631703 @default.
- W2079888510 hasRelatedWork W2122686314 @default.
- W2079888510 hasRelatedWork W2147741187 @default.
- W2079888510 hasVolume "21" @default.
- W2079888510 isParatext "false" @default.
- W2079888510 isRetracted "false" @default.
- W2079888510 magId "2079888510" @default.
- W2079888510 workType "article" @default.