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- W2079897076 abstract "Two radioimmunoassays for human lactalbumin have been established using a rabbit antiserum. One assay uses a second antibody to separate bound from free label; the other uses polyethylene glycol to precipitate gamma globulin non-specifically. We have confirmed that about half the normal human population have a substance in their blood which inhibits the binding of lactalbumin to the rabbit antibody. Comparison of the two assays has demonstrated that this material is not lactalbumin but a naturally occurring antibody. We have shown that it is in the IgG fraction of human plasma and is probably a crossreacting antibody to bovine lactalbumin. None out of fifteen males and fourteen out of fifty eight non-pregnant, non-lactating females had low levels of lactalbumin in their blood (0.6–2.0 ng/ml). Our assay could not detect a statistically significant difference between normal women and those with either benign breast disease or metastatic mammary carcinoma." @default.
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- W2079897076 date "1978-07-01" @default.
- W2079897076 modified "2023-09-27" @default.
- W2079897076 title "Antibodies to lactalbumin interfere with its radioimmunoassay in human plasma" @default.
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- W2079897076 doi "https://doi.org/10.1016/0009-8981(78)90069-4" @default.
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