FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2079897245> ?p ?o ?g. }

• W2079897245 endingPage "531" @default.
• W2079897245 startingPage "525" @default.
• W2079897245 abstract "Thymic stromal lymphopoietin (TSLP) is a cytokine implicated in the pathogenesis of allergic diseases such as asthma, atopic dermatitis and allergic rhinitis. Curcumin has various effects such as antidepressant, antioxidant, antihyperglycemic, antitumor and anti-inflammatory. However, the effect of curcumin on the production of TSLP has not been clarified. Thus, we investigated how curcumin inhibits the expression and production of TSLP in the human mast cell line, HMC-1 cells. We used enzyme-linked immunosorbent assay, reverse transcription-polymerase chain reaction, luciferase assay, and caspase-1 assay to investigate the effects of curcumin. The results show that curcumin inhibited the production and mRNAexpression of TSLP in HMC-1 cells: the maximal inhibition rate of TSLP production by curcumin (50 ìM) was 59.16 ± 4.20%. In addition, curcumin suppressed the nuclear factor-kB luciferase activity induced by phorbol myristate acetate plus A23187. In the activated HMC-1 cells, caspase-1 activity was increased, whereas caspase-1 activity was decreased by pretreatment with curcumin. These results suggest that curcumin can be used to treat inflammatory and atopic diseases through the suppression of TSLP." @default.
• W2079897245 created "2016-06-24" @default.
• W2079897245 creator A5046879145 @default.
• W2079897245 creator A5049541329 @default.
• W2079897245 creator A5071734744 @default.
• W2079897245 date "2013-03-01" @default.
• W2079897245 modified "2023-10-17" @default.
• W2079897245 title "Down-regulation of thymic stromal lymphopoietin by curcumin" @default.
• W2079897245 cites W1546009103 @default.
• W2079897245 cites W1823764983 @default.
• W2079897245 cites W1878755986 @default.
• W2079897245 cites W1973462214 @default.
• W2079897245 cites W1981232450 @default.
• W2079897245 cites W1991656827 @default.
• W2079897245 cites W2007176059 @default.
• W2079897245 cites W2010852340 @default.
• W2079897245 cites W2012947457 @default.
• W2079897245 cites W2013279472 @default.
• W2079897245 cites W2016704574 @default.
• W2079897245 cites W2030186278 @default.
• W2079897245 cites W2034066156 @default.
• W2079897245 cites W2043340777 @default.
• W2079897245 cites W2043987447 @default.
• W2079897245 cites W2061092989 @default.
• W2079897245 cites W2087543974 @default.
• W2079897245 cites W2088322976 @default.
• W2079897245 cites W2105496579 @default.
• W2079897245 cites W2107256985 @default.
• W2079897245 cites W2108622639 @default.
• W2079897245 cites W2128104539 @default.
• W2079897245 cites W2136339403 @default.
• W2079897245 cites W2136636771 @default.
• W2079897245 cites W2136918536 @default.
• W2079897245 cites W2140040520 @default.
• W2079897245 cites W2142940006 @default.
• W2079897245 cites W2146979059 @default.
• W2079897245 cites W4232685799 @default.
• W2079897245 cites W4246115033 @default.
• W2079897245 doi "https://doi.org/10.1016/s1734-1140(13)71029-6" @default.
• W2079897245 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/23744438" @default.
• W2079897245 hasPublicationYear "2013" @default.
• W2079897245 type Work @default.
• W2079897245 sameAs 2079897245 @default.
• W2079897245 citedByCount "14" @default.
• W2079897245 countsByYear W20798972452014 @default.
• W2079897245 countsByYear W20798972452015 @default.
• W2079897245 countsByYear W20798972452016 @default.
• W2079897245 countsByYear W20798972452017 @default.
• W2079897245 countsByYear W20798972452018 @default.
• W2079897245 countsByYear W20798972452019 @default.
• W2079897245 countsByYear W20798972452020 @default.
• W2079897245 countsByYear W20798972452023 @default.
• W2079897245 crossrefType "journal-article" @default.
• W2079897245 hasAuthorship W2079897245A5046879145 @default.
• W2079897245 hasAuthorship W2079897245A5049541329 @default.
• W2079897245 hasAuthorship W2079897245A5071734744 @default.
• W2079897245 hasBestOaLocation W20798972452 @default.
• W2079897245 hasConcept C104317684 @default.
• W2079897245 hasConcept C111335760 @default.
• W2079897245 hasConcept C139964883 @default.
• W2079897245 hasConcept C185592680 @default.
• W2079897245 hasConcept C190283241 @default.
• W2079897245 hasConcept C203014093 @default.
• W2079897245 hasConcept C2778070265 @default.
• W2079897245 hasConcept C2778250585 @default.
• W2079897245 hasConcept C2778690821 @default.
• W2079897245 hasConcept C31573885 @default.
• W2079897245 hasConcept C54009773 @default.
• W2079897245 hasConcept C55493867 @default.
• W2079897245 hasConcept C71924100 @default.
• W2079897245 hasConcept C74172505 @default.
• W2079897245 hasConcept C98274493 @default.
• W2079897245 hasConceptScore W2079897245C104317684 @default.
• W2079897245 hasConceptScore W2079897245C111335760 @default.
• W2079897245 hasConceptScore W2079897245C139964883 @default.
• W2079897245 hasConceptScore W2079897245C185592680 @default.
• W2079897245 hasConceptScore W2079897245C190283241 @default.
• W2079897245 hasConceptScore W2079897245C203014093 @default.
• W2079897245 hasConceptScore W2079897245C2778070265 @default.
• W2079897245 hasConceptScore W2079897245C2778250585 @default.
• W2079897245 hasConceptScore W2079897245C2778690821 @default.
• W2079897245 hasConceptScore W2079897245C31573885 @default.
• W2079897245 hasConceptScore W2079897245C54009773 @default.
• W2079897245 hasConceptScore W2079897245C55493867 @default.
• W2079897245 hasConceptScore W2079897245C71924100 @default.
• W2079897245 hasConceptScore W2079897245C74172505 @default.
• W2079897245 hasConceptScore W2079897245C98274493 @default.
• W2079897245 hasIssue "2" @default.
• W2079897245 hasLocation W20798972451 @default.
• W2079897245 hasLocation W20798972452 @default.
• W2079897245 hasLocation W20798972453 @default.
• W2079897245 hasOpenAccess W2079897245 @default.
• W2079897245 hasPrimaryLocation W20798972451 @default.
• W2079897245 hasRelatedWork W1596808811 @default.
• W2079897245 hasRelatedWork W2038011147 @default.
• W2079897245 hasRelatedWork W2069935301 @default.
• W2079897245 hasRelatedWork W2077917566 @default.
• W2079897245 hasRelatedWork W2079897245 @default.

• next