FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2079928619> ?p ?o ?g. }

• W2079928619 endingPage "962" @default.
• W2079928619 startingPage "954" @default.
• W2079928619 abstract "Aspergillus fumigatus is a mold causing most of the invasive fungal lung infections in the immunocompromised host. In addition, the species is the causative agent of certain allergic diseases. Both in invasive and in allergic diseases, the conidial surface mediates the first contact with the human immune system. Thus, conidial surface proteins may be reasonable vaccine candidates as well as important allergens. To broaden the list of those antigens, intact viable Aspergillus conidia were extracted with mild alkaline buffer at pH 8.5 in the presence of a 1,3-β-glucanase. The proteome of this fraction was separated by two- dimensional gel electrophoresis (2-DE) and analyzed by liquid chromatography coupled with tandem mass spectrometry. Altogether 26 different A. fumigatus proteins were identified, twelve of which contain a signal for secretion. Among these were the known major conidial surface protein rodlet A, one acid protease PEP2, one lipase, a putative disulfide isomerase and a putative fructose-1,6-biphosphatase. The known allergen Aspf 3 was identified among the proteins without a signal for secretion. On the basis of the recently annotated A. fumigatus genome (Nature 2005, 438, 1151−1156), proteome analysis is now a powerful tool to confirm expression of hypothetical proteins and, thereby to identify additional vaccine candidates and possible new allergens of this important fungal pathogen. Keywords: A. fumigatus • proteome • conidia • conidial surface • vaccine • allergens" @default.
• W2079928619 created "2016-06-24" @default.
• W2079928619 creator A5016061371 @default.
• W2079928619 creator A5036614893 @default.
• W2079928619 creator A5043789562 @default.
• W2079928619 creator A5055085283 @default.
• W2079928619 creator A5075412773 @default.
• W2079928619 creator A5077227657 @default.
• W2079928619 date "2006-03-01" @default.
• W2079928619 modified "2023-10-02" @default.
• W2079928619 title "Proteome of Conidial Surface Associated Proteins of <i>Aspergillus </i><i>f</i><i>umigatus</i> Reflecting Potential Vaccine Candidates and Allergens" @default.
• W2079928619 cites W1771141216 @default.
• W2079928619 cites W1935733700 @default.
• W2079928619 cites W1936973185 @default.
• W2079928619 cites W1966977439 @default.
• W2079928619 cites W1970880679 @default.
• W2079928619 cites W1989738506 @default.
• W2079928619 cites W1999463404 @default.
• W2079928619 cites W2004589024 @default.
• W2079928619 cites W2006797063 @default.
• W2079928619 cites W2019749697 @default.
• W2079928619 cites W2036402189 @default.
• W2079928619 cites W2056290410 @default.
• W2079928619 cites W2069849131 @default.
• W2079928619 cites W2084481741 @default.
• W2079928619 cites W2088693217 @default.
• W2079928619 cites W2088935771 @default.
• W2079928619 cites W2090756504 @default.
• W2079928619 cites W2106551616 @default.
• W2079928619 cites W2108313755 @default.
• W2079928619 cites W2123659189 @default.
• W2079928619 cites W2126476096 @default.
• W2079928619 cites W2136735616 @default.
• W2079928619 cites W2144528224 @default.
• W2079928619 cites W2149288225 @default.
• W2079928619 cites W2153911335 @default.
• W2079928619 cites W2154719091 @default.
• W2079928619 cites W2157839115 @default.
• W2079928619 cites W2166075607 @default.
• W2079928619 cites W2171777893 @default.
• W2079928619 cites W4230924492 @default.
• W2079928619 cites W4293247451 @default.
• W2079928619 cites W4297852198 @default.
• W2079928619 doi "https://doi.org/10.1021/pr0504586" @default.
• W2079928619 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/16602703" @default.
• W2079928619 hasPublicationYear "2006" @default.
• W2079928619 type Work @default.
• W2079928619 sameAs 2079928619 @default.
• W2079928619 citedByCount "111" @default.
• W2079928619 countsByYear W20799286192012 @default.
• W2079928619 countsByYear W20799286192013 @default.
• W2079928619 countsByYear W20799286192014 @default.
• W2079928619 countsByYear W20799286192015 @default.
• W2079928619 countsByYear W20799286192016 @default.
• W2079928619 countsByYear W20799286192017 @default.
• W2079928619 countsByYear W20799286192018 @default.
• W2079928619 countsByYear W20799286192019 @default.
• W2079928619 countsByYear W20799286192020 @default.
• W2079928619 countsByYear W20799286192021 @default.
• W2079928619 countsByYear W20799286192022 @default.
• W2079928619 countsByYear W20799286192023 @default.
• W2079928619 crossrefType "journal-article" @default.
• W2079928619 hasAuthorship W2079928619A5016061371 @default.
• W2079928619 hasAuthorship W2079928619A5036614893 @default.
• W2079928619 hasAuthorship W2079928619A5043789562 @default.
• W2079928619 hasAuthorship W2079928619A5055085283 @default.
• W2079928619 hasAuthorship W2079928619A5075412773 @default.
• W2079928619 hasAuthorship W2079928619A5077227657 @default.
• W2079928619 hasConcept C104397665 @default.
• W2079928619 hasConcept C185592680 @default.
• W2079928619 hasConcept C203014093 @default.
• W2079928619 hasConcept C207480886 @default.
• W2079928619 hasConcept C2776460866 @default.
• W2079928619 hasConcept C2779175654 @default.
• W2079928619 hasConcept C2779787849 @default.
• W2079928619 hasConcept C2780510475 @default.
• W2079928619 hasConcept C55493867 @default.
• W2079928619 hasConcept C86803240 @default.
• W2079928619 hasConcept C89423630 @default.
• W2079928619 hasConceptScore W2079928619C104397665 @default.
• W2079928619 hasConceptScore W2079928619C185592680 @default.
• W2079928619 hasConceptScore W2079928619C203014093 @default.
• W2079928619 hasConceptScore W2079928619C207480886 @default.
• W2079928619 hasConceptScore W2079928619C2776460866 @default.
• W2079928619 hasConceptScore W2079928619C2779175654 @default.
• W2079928619 hasConceptScore W2079928619C2779787849 @default.
• W2079928619 hasConceptScore W2079928619C2780510475 @default.
• W2079928619 hasConceptScore W2079928619C55493867 @default.
• W2079928619 hasConceptScore W2079928619C86803240 @default.
• W2079928619 hasConceptScore W2079928619C89423630 @default.
• W2079928619 hasIssue "4" @default.
• W2079928619 hasLocation W20799286191 @default.
• W2079928619 hasLocation W20799286192 @default.
• W2079928619 hasOpenAccess W2079928619 @default.
• W2079928619 hasPrimaryLocation W20799286191 @default.
• W2079928619 hasRelatedWork W2026627716 @default.
• W2079928619 hasRelatedWork W2062531300 @default.
• W2079928619 hasRelatedWork W2075407703 @default.

• next