Matches in SemOpenAlex for { <https://semopenalex.org/work/W2079938067> ?p ?o ?g. }
Showing items 1 to 100 of
100
with 100 items per page.
- W2079938067 endingPage "640" @default.
- W2079938067 startingPage "631" @default.
- W2079938067 abstract "The presynaptic effects of beta-bungarotoxin, crotoxin and taipoxin were studied in the mouse phrenic nerve-diaphragm preparation (27 degrees C). The phospholipase A2 activity, assayed by pH-stat titration, was reduced to 4-10% at 27 degrees C compared with that at 37 degrees C. The late neuromuscular blocking activity was also reduced by more than three fold for all toxins. In contrast, the early biphasic response to the toxins, i.e. immediate depression followed by facilitation, was not delayed. The evoked quantal release of acetylcholine was enhanced by all toxins at low Ca2+-concentrations during the phase of facilitation, without an increase of the maximal release. At the late phase of treatment with beta-bungarotoxin and taipoxin, the curve relating the quantal contents of endplate potentials with Ca2+-concentration was shifted parallel to the right at low Ca2+, but marked depression of the maximal release occurred at high Ca2+. When diaminopyridine was added at the time of the late phase block by beta-bungarotoxin, the quantal release could still be enhanced at low Ca2+-concentrations, even beyond control; however, the maximal release was not simultaneously restored. It is concluded that the late phase block, but not the early biphasic response, is due to an enzymatic action and the release mechanism is abolished when the hydrolysis of membrane phospholipids proceeds to a certain critical level." @default.
- W2079938067 created "2016-06-24" @default.
- W2079938067 creator A5002896915 @default.
- W2079938067 creator A5079021524 @default.
- W2079938067 date "1984-01-01" @default.
- W2079938067 modified "2023-10-17" @default.
- W2079938067 title "Presynaptic effects of snake venom toxins which have phospholipase A2 activity (β-bungarotoxin, taipoxin, crotoxin)" @default.
- W2079938067 cites W1579677476 @default.
- W2079938067 cites W1588730657 @default.
- W2079938067 cites W1967062857 @default.
- W2079938067 cites W1967398142 @default.
- W2079938067 cites W1969164617 @default.
- W2079938067 cites W1969895486 @default.
- W2079938067 cites W1971025385 @default.
- W2079938067 cites W1981606586 @default.
- W2079938067 cites W1988179016 @default.
- W2079938067 cites W1998299134 @default.
- W2079938067 cites W2002142711 @default.
- W2079938067 cites W2015905038 @default.
- W2079938067 cites W2023530114 @default.
- W2079938067 cites W2028513419 @default.
- W2079938067 cites W2039766497 @default.
- W2079938067 cites W2040951237 @default.
- W2079938067 cites W2046456016 @default.
- W2079938067 cites W2054530577 @default.
- W2079938067 cites W2106081526 @default.
- W2079938067 cites W2116304547 @default.
- W2079938067 doi "https://doi.org/10.1016/0041-0101(84)90003-5" @default.
- W2079938067 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/6089381" @default.
- W2079938067 hasPublicationYear "1984" @default.
- W2079938067 type Work @default.
- W2079938067 sameAs 2079938067 @default.
- W2079938067 citedByCount "66" @default.
- W2079938067 countsByYear W20799380672012 @default.
- W2079938067 countsByYear W20799380672013 @default.
- W2079938067 countsByYear W20799380672015 @default.
- W2079938067 countsByYear W20799380672016 @default.
- W2079938067 countsByYear W20799380672017 @default.
- W2079938067 countsByYear W20799380672018 @default.
- W2079938067 countsByYear W20799380672019 @default.
- W2079938067 countsByYear W20799380672020 @default.
- W2079938067 countsByYear W20799380672021 @default.
- W2079938067 countsByYear W20799380672022 @default.
- W2079938067 crossrefType "journal-article" @default.
- W2079938067 hasAuthorship W2079938067A5002896915 @default.
- W2079938067 hasAuthorship W2079938067A5079021524 @default.
- W2079938067 hasConcept C12554922 @default.
- W2079938067 hasConcept C126322002 @default.
- W2079938067 hasConcept C12927208 @default.
- W2079938067 hasConcept C134018914 @default.
- W2079938067 hasConcept C170493617 @default.
- W2079938067 hasConcept C181199279 @default.
- W2079938067 hasConcept C185592680 @default.
- W2079938067 hasConcept C2775910092 @default.
- W2079938067 hasConcept C2776551241 @default.
- W2079938067 hasConcept C2776888444 @default.
- W2079938067 hasConcept C2777186327 @default.
- W2079938067 hasConcept C2779448229 @default.
- W2079938067 hasConcept C55493867 @default.
- W2079938067 hasConcept C71924100 @default.
- W2079938067 hasConcept C80161118 @default.
- W2079938067 hasConcept C86803240 @default.
- W2079938067 hasConceptScore W2079938067C12554922 @default.
- W2079938067 hasConceptScore W2079938067C126322002 @default.
- W2079938067 hasConceptScore W2079938067C12927208 @default.
- W2079938067 hasConceptScore W2079938067C134018914 @default.
- W2079938067 hasConceptScore W2079938067C170493617 @default.
- W2079938067 hasConceptScore W2079938067C181199279 @default.
- W2079938067 hasConceptScore W2079938067C185592680 @default.
- W2079938067 hasConceptScore W2079938067C2775910092 @default.
- W2079938067 hasConceptScore W2079938067C2776551241 @default.
- W2079938067 hasConceptScore W2079938067C2776888444 @default.
- W2079938067 hasConceptScore W2079938067C2777186327 @default.
- W2079938067 hasConceptScore W2079938067C2779448229 @default.
- W2079938067 hasConceptScore W2079938067C55493867 @default.
- W2079938067 hasConceptScore W2079938067C71924100 @default.
- W2079938067 hasConceptScore W2079938067C80161118 @default.
- W2079938067 hasConceptScore W2079938067C86803240 @default.
- W2079938067 hasIssue "4" @default.
- W2079938067 hasLocation W20799380671 @default.
- W2079938067 hasLocation W20799380672 @default.
- W2079938067 hasOpenAccess W2079938067 @default.
- W2079938067 hasPrimaryLocation W20799380671 @default.
- W2079938067 hasRelatedWork W1965116143 @default.
- W2079938067 hasRelatedWork W1974743394 @default.
- W2079938067 hasRelatedWork W1986153789 @default.
- W2079938067 hasRelatedWork W2019816897 @default.
- W2079938067 hasRelatedWork W2057403631 @default.
- W2079938067 hasRelatedWork W2059596269 @default.
- W2079938067 hasRelatedWork W2089511140 @default.
- W2079938067 hasRelatedWork W2355849535 @default.
- W2079938067 hasRelatedWork W2975155290 @default.
- W2079938067 hasRelatedWork W2993167739 @default.
- W2079938067 hasVolume "22" @default.
- W2079938067 isParatext "false" @default.
- W2079938067 isRetracted "false" @default.
- W2079938067 magId "2079938067" @default.
- W2079938067 workType "article" @default.