Matches in SemOpenAlex for { <https://semopenalex.org/work/W2079956029> ?p ?o ?g. }
- W2079956029 endingPage "1025" @default.
- W2079956029 startingPage "1018" @default.
- W2079956029 abstract "The present study aimed to describe the distribution and features of the SYT-SSX fusion gene in Chinese patients with synovial sarcoma (SS), and to analyze the prognostic value of SYT-SSX fusion type and clinicopathological parameters for tumor-related death, recurrence, and metastasis in SS. SYT-SSX1 and SYT-SSX2 fusion transcripts were tested by reverse transcription-polymerase chain reaction in 141 formalin-fixed, paraffin-embedded SS. The prognostic implication of SYT-SSX fusion type and clinicopathological parameters were analyzed by univariate and multivariate survival analyses. SYT-SSX1 and SYT-SSX2 were detected in 50 (34.5%) and 91 (64.5%) tumors, respectively. SYT-SSX1 (risk ratio [RR] = 2.032, P = 0.004), larger tumor size (RR = 1.859, P = 0.008), and aggressive Fédération Nationale des Centers de Lutte Contre le Cancer grade (RR = 2.094, P = 0.001) were adverse predictors for disease-specific survival. However, SYT-SSX fusion type was not associated with local recurrence-free survival (P = 0.216). Patients with larger tumors (RR = 2.071, P = 0.005) and those who received marginal excision (RR = 2.556, P = 0.005) had poor local recurrence-free survival. Besides, SYT-SSX1 (RR = 1.859, P = 0.037), older age (RR = 1.799, P = 0.040), and aggressive International Union Against Cancer stage (RR = 3.690, P < 0.001) proved to be adverse prognostic factors for metastasis-free survival. In conclusion, compared to SYT-SSX1, SYT-SSX2 was more frequent in Chinese patients with SS. Moreover, SYT-SSX1 was an adverse predictor for disease-specific survival and metastasis-free survival, but had no relation to local recurrence-free survival. In addition, histological grade and tumor size were also important prognostic factors for SS." @default.
- W2079956029 created "2016-06-24" @default.
- W2079956029 creator A5025910593 @default.
- W2079956029 creator A5032764121 @default.
- W2079956029 creator A5049567302 @default.
- W2079956029 creator A5049782349 @default.
- W2079956029 creator A5061049387 @default.
- W2079956029 creator A5061089773 @default.
- W2079956029 creator A5063983172 @default.
- W2079956029 date "2009-05-20" @default.
- W2079956029 modified "2023-10-15" @default.
- W2079956029 title "Prognostic implication of SYT-SSX fusion type and clinicopathological parameters for tumor-related death, recurrence, and metastasis in synovial sarcoma" @default.
- W2079956029 cites W1492124857 @default.
- W2079956029 cites W1892581571 @default.
- W2079956029 cites W1909079918 @default.
- W2079956029 cites W1959758810 @default.
- W2079956029 cites W1977872851 @default.
- W2079956029 cites W1979870208 @default.
- W2079956029 cites W1980314947 @default.
- W2079956029 cites W1983206829 @default.
- W2079956029 cites W1984740535 @default.
- W2079956029 cites W1984825781 @default.
- W2079956029 cites W1993256497 @default.
- W2079956029 cites W1998874145 @default.
- W2079956029 cites W2003478678 @default.
- W2079956029 cites W2011370351 @default.
- W2079956029 cites W2013696012 @default.
- W2079956029 cites W2045661738 @default.
- W2079956029 cites W2061172839 @default.
- W2079956029 cites W2068868961 @default.
- W2079956029 cites W2077718835 @default.
- W2079956029 cites W2079275433 @default.
- W2079956029 cites W2081628846 @default.
- W2079956029 cites W2092684427 @default.
- W2079956029 cites W2096187053 @default.
- W2079956029 cites W2100135066 @default.
- W2079956029 cites W2118475754 @default.
- W2079956029 cites W2121446024 @default.
- W2079956029 cites W2127067652 @default.
- W2079956029 cites W2149285292 @default.
- W2079956029 cites W2155978618 @default.
- W2079956029 cites W2318344307 @default.
- W2079956029 cites W4253220361 @default.
- W2079956029 cites W4297671809 @default.
- W2079956029 doi "https://doi.org/10.1111/j.1349-7006.2009.01134.x" @default.
- W2079956029 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/19385976" @default.
- W2079956029 hasPublicationYear "2009" @default.
- W2079956029 type Work @default.
- W2079956029 sameAs 2079956029 @default.
- W2079956029 citedByCount "32" @default.
- W2079956029 countsByYear W20799560292012 @default.
- W2079956029 countsByYear W20799560292013 @default.
- W2079956029 countsByYear W20799560292014 @default.
- W2079956029 countsByYear W20799560292015 @default.
- W2079956029 countsByYear W20799560292016 @default.
- W2079956029 countsByYear W20799560292017 @default.
- W2079956029 countsByYear W20799560292018 @default.
- W2079956029 countsByYear W20799560292020 @default.
- W2079956029 countsByYear W20799560292021 @default.
- W2079956029 countsByYear W20799560292022 @default.
- W2079956029 countsByYear W20799560292023 @default.
- W2079956029 crossrefType "journal-article" @default.
- W2079956029 hasAuthorship W2079956029A5025910593 @default.
- W2079956029 hasAuthorship W2079956029A5032764121 @default.
- W2079956029 hasAuthorship W2079956029A5049567302 @default.
- W2079956029 hasAuthorship W2079956029A5049782349 @default.
- W2079956029 hasAuthorship W2079956029A5061049387 @default.
- W2079956029 hasAuthorship W2079956029A5061089773 @default.
- W2079956029 hasAuthorship W2079956029A5063983172 @default.
- W2079956029 hasBestOaLocation W20799560291 @default.
- W2079956029 hasConcept C104317684 @default.
- W2079956029 hasConcept C111829193 @default.
- W2079956029 hasConcept C121608353 @default.
- W2079956029 hasConcept C126322002 @default.
- W2079956029 hasConcept C142724271 @default.
- W2079956029 hasConcept C143998085 @default.
- W2079956029 hasConcept C144301174 @default.
- W2079956029 hasConcept C197934379 @default.
- W2079956029 hasConcept C2776910622 @default.
- W2079956029 hasConcept C2778256501 @default.
- W2079956029 hasConcept C2779013556 @default.
- W2079956029 hasConcept C38180746 @default.
- W2079956029 hasConcept C502942594 @default.
- W2079956029 hasConcept C54355233 @default.
- W2079956029 hasConcept C71924100 @default.
- W2079956029 hasConcept C86803240 @default.
- W2079956029 hasConceptScore W2079956029C104317684 @default.
- W2079956029 hasConceptScore W2079956029C111829193 @default.
- W2079956029 hasConceptScore W2079956029C121608353 @default.
- W2079956029 hasConceptScore W2079956029C126322002 @default.
- W2079956029 hasConceptScore W2079956029C142724271 @default.
- W2079956029 hasConceptScore W2079956029C143998085 @default.
- W2079956029 hasConceptScore W2079956029C144301174 @default.
- W2079956029 hasConceptScore W2079956029C197934379 @default.
- W2079956029 hasConceptScore W2079956029C2776910622 @default.
- W2079956029 hasConceptScore W2079956029C2778256501 @default.
- W2079956029 hasConceptScore W2079956029C2779013556 @default.
- W2079956029 hasConceptScore W2079956029C38180746 @default.