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- W207996776 abstract "Prion diseases caused by the conversion from a soluble normal cellular prion protein into insoluble abnormally folded infectious prions, are invariably fatal and highly infectious degenerative diseases that affect a wide variety of mammalian species. The palindrome and the Glycine-rich conserved segment in the hydrophobic region 109-136 control the conversion from normal prion protein to form into diseased prions. This paper gives detailed reviews on the 109-136 region and presents the studies of its 3D structures and structural dynamics." @default.
- W207996776 created "2016-06-24" @default.
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- W207996776 date "2013-01-01" @default.
- W207996776 modified "2023-09-27" @default.
- W207996776 title "Computational Studies on the Molecular Structure of the Hydrophobic Region PrP 109-136" @default.
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