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- W2079968019 abstract "We have applied electrophoresis on agarose gels to investigate the DNA-binding capacity of cationic liposomes made of cationic DC-cholesterol and neutral dioleoylphosphatidylethanolamine as a function of membrane charge density and cationic lipid/DNA charge ratio. While each cationic liposome formulation exhibits a distinctive DNA-protection ability, here we show that such a capacity is universally regulated by surface area of lipid membranes available for binding in an aspecific manner. The relevance of DNA protection for gene transfection is also discussed." @default.
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- W2079968019 date "2009-01-19" @default.
- W2079968019 modified "2023-09-30" @default.
- W2079968019 title "Surface area of lipid membranes regulates the DNA-binding capacity of cationic liposomes" @default.
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- W2079968019 doi "https://doi.org/10.1063/1.3074444" @default.
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