FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2080002009> ?p ?o ?g. }

• W2080002009 endingPage "366" @default.
• W2080002009 startingPage "355" @default.
• W2080002009 abstract "Bone is subject to continuous remodeling throughout life. The age-related loss of (trabecular) bone, leading to senile osteopenia, is mainly due to impaired bone formation. Osteoblasts (OB) and osteoclasts (OC) have been identified as playing a crucial role in the process of bone turnover, but the contribution made by their precursors is not well documented. We analyzed the cells of the osteoblast and osteoclast cell lineage along the trabecular bone of tibiae and the stromal cells in the marrow of aging BN/Bi Rij rats using electron microscopy. It appeared possible to distinguish preosteoblasts (pre-OB), OB, preosteoclasts (pre-OC), OC, and inactive bone-lining cells. Periods of increase, the maximal peak, and the decrease in trabecular bone volume were defined by means of morphometric measurements of trabecular bone volume. We found a decrease of more than 10-fold in the number of OB with age, but the numbers of pre-OB, pre-OC, and OC expressed per unit bone length, although variable, were age independent. The relative bone resorption and formation surface, expressed as a percentage of the total bone surface, decreased 2- and 15-fold, respectively. In 2-year-old animals the total volume of stromal cells, part of which constitutes the stem cell compartment of the osteogenic lineage, was a quarter of that found in 1-month-old animals and a third of that found in 6-month-old animals. The loss of trabecular bone is concomitant with a sharp increase in the ratio of pre-OB/OB, the ratio of OC/OB, and in the ratio of resorption to formation surfaces. There was no relation between the ratio of pre-OC/OC with age. These data lead to the conclusion that the main factor causing bone loss with age is a diminished maturation of pre-OB into OB." @default.
• W2080002009 created "2016-06-24" @default.
• W2080002009 creator A5003603745 @default.
• W2080002009 creator A5007256934 @default.
• W2080002009 creator A5027634539 @default.
• W2080002009 creator A5029942950 @default.
• W2080002009 creator A5082192614 @default.
• W2080002009 date "2009-12-03" @default.
• W2080002009 modified "2023-10-17" @default.
• W2080002009 title "Evidence for a diminished maturation of preosteoblasts into osteoblasts during aging in rats: An ultrastructural analysis" @default.
• W2080002009 cites W1967492863 @default.
• W2080002009 cites W1972376518 @default.
• W2080002009 cites W1973830769 @default.
• W2080002009 cites W1976104407 @default.
• W2080002009 cites W1986484374 @default.
• W2080002009 cites W2005097199 @default.
• W2080002009 cites W2005706897 @default.
• W2080002009 cites W2020075378 @default.
• W2080002009 cites W2033467001 @default.
• W2080002009 cites W2070669279 @default.
• W2080002009 cites W2073861563 @default.
• W2080002009 cites W2075827517 @default.
• W2080002009 cites W2080741216 @default.
• W2080002009 cites W2083081277 @default.
• W2080002009 cites W2088640839 @default.
• W2080002009 cites W2091423691 @default.
• W2080002009 cites W2104161119 @default.
• W2080002009 cites W2118676056 @default.
• W2080002009 cites W2125725130 @default.
• W2080002009 cites W2144268541 @default.
• W2080002009 cites W2162552372 @default.
• W2080002009 cites W2341699965 @default.
• W2080002009 doi "https://doi.org/10.1002/jbmr.5650090310" @default.
• W2080002009 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/8191929" @default.
• W2080002009 hasPublicationYear "2009" @default.
• W2080002009 type Work @default.
• W2080002009 sameAs 2080002009 @default.
• W2080002009 citedByCount "114" @default.
• W2080002009 countsByYear W20800020092012 @default.
• W2080002009 countsByYear W20800020092013 @default.
• W2080002009 countsByYear W20800020092014 @default.
• W2080002009 countsByYear W20800020092015 @default.
• W2080002009 countsByYear W20800020092016 @default.
• W2080002009 countsByYear W20800020092017 @default.
• W2080002009 countsByYear W20800020092018 @default.
• W2080002009 countsByYear W20800020092019 @default.
• W2080002009 countsByYear W20800020092020 @default.
• W2080002009 countsByYear W20800020092021 @default.
• W2080002009 countsByYear W20800020092022 @default.
• W2080002009 countsByYear W20800020092023 @default.
• W2080002009 crossrefType "journal-article" @default.
• W2080002009 hasAuthorship W2080002009A5003603745 @default.
• W2080002009 hasAuthorship W2080002009A5007256934 @default.
• W2080002009 hasAuthorship W2080002009A5027634539 @default.
• W2080002009 hasAuthorship W2080002009A5029942950 @default.
• W2080002009 hasAuthorship W2080002009A5082192614 @default.
• W2080002009 hasConcept C126322002 @default.
• W2080002009 hasConcept C133605539 @default.
• W2080002009 hasConcept C134018914 @default.
• W2080002009 hasConcept C146562846 @default.
• W2080002009 hasConcept C16930146 @default.
• W2080002009 hasConcept C170033053 @default.
• W2080002009 hasConcept C170493617 @default.
• W2080002009 hasConcept C185592680 @default.
• W2080002009 hasConcept C202751555 @default.
• W2080002009 hasConcept C2776033226 @default.
• W2080002009 hasConcept C2776541429 @default.
• W2080002009 hasConcept C2776886416 @default.
• W2080002009 hasConcept C2777083390 @default.
• W2080002009 hasConcept C2778260815 @default.
• W2080002009 hasConcept C2780007613 @default.
• W2080002009 hasConcept C55493867 @default.
• W2080002009 hasConcept C673006 @default.
• W2080002009 hasConcept C71924100 @default.
• W2080002009 hasConcept C86803240 @default.
• W2080002009 hasConceptScore W2080002009C126322002 @default.
• W2080002009 hasConceptScore W2080002009C133605539 @default.
• W2080002009 hasConceptScore W2080002009C134018914 @default.
• W2080002009 hasConceptScore W2080002009C146562846 @default.
• W2080002009 hasConceptScore W2080002009C16930146 @default.
• W2080002009 hasConceptScore W2080002009C170033053 @default.
• W2080002009 hasConceptScore W2080002009C170493617 @default.
• W2080002009 hasConceptScore W2080002009C185592680 @default.
• W2080002009 hasConceptScore W2080002009C202751555 @default.
• W2080002009 hasConceptScore W2080002009C2776033226 @default.
• W2080002009 hasConceptScore W2080002009C2776541429 @default.
• W2080002009 hasConceptScore W2080002009C2776886416 @default.
• W2080002009 hasConceptScore W2080002009C2777083390 @default.
• W2080002009 hasConceptScore W2080002009C2778260815 @default.
• W2080002009 hasConceptScore W2080002009C2780007613 @default.
• W2080002009 hasConceptScore W2080002009C55493867 @default.
• W2080002009 hasConceptScore W2080002009C673006 @default.
• W2080002009 hasConceptScore W2080002009C71924100 @default.
• W2080002009 hasConceptScore W2080002009C86803240 @default.
• W2080002009 hasIssue "3" @default.
• W2080002009 hasLocation W20800020091 @default.
• W2080002009 hasLocation W20800020092 @default.
• W2080002009 hasOpenAccess W2080002009 @default.

• next