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- W2080046617 abstract "Abstract Glucose and amino acid-stimulated insulin release was studied in vivo in cannulated European silver eels ( Anguilla anguilla ). Glucose-stimulated insulin release was dose dependent over a range of glucose loads (10–100 mg/kg) while higher doses (300 and 500 mg/kg) produced no greater increments than 100 mg/kg. Arginine and lysine injections of 10, 25 and 100 mg/kg caused greater significant increases in plasma insulin levels than glucose at the same dose levels. Histidine (10 and 25 mg/kg) caused a small but significant reduction in the plasma insulin level. Simultaneous injection of arginine (100 mg/kg) and glucose (100 mg/kg) caused an increase in plasma insulin which was sustained for 60 min and remained significantly above the controls over the 360 min sampling period. Total insulin secretion appeared to be significantly greater over the entire sampling period than when arginine and glucose were injected alone." @default.
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- W2080046617 date "1977-02-01" @default.
- W2080046617 modified "2023-09-25" @default.
- W2080046617 title "Glucose and amino acid-stimulated insulin release in vivo in the European silver eel (Anguilla anguilla L.)" @default.
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- W2080046617 doi "https://doi.org/10.1016/0016-6480(77)90024-7" @default.
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