Matches in SemOpenAlex for { <https://semopenalex.org/work/W2080071375> ?p ?o ?g. }
- W2080071375 endingPage "1189" @default.
- W2080071375 startingPage "1177" @default.
- W2080071375 abstract "The crystal structure of Thermotoga maritima NusA, a transcription factor involved in pausing, termination, and antitermination processes, reveals a four-domain, rod-shaped molecule. An N-terminal α/β portion, a five-stranded β-barrel (S1 domain), and two K-homology (KH) modules create a continuous spine of positive electrostatic potential, suitable for nonspecific mRNA attraction. Homology models suggest how, in addition, specific mRNA regulatory sequences can be recognized by the S1 and KH motifs. An arrangement of multiple S1 and KH domains mediated by highly conserved residues is seen, creating an extended RNA binding surface, a paradigm for other proteins with similar domain arrays. Structural and mutational analyses indicate that the motifs cooperate, modulating strength and specificity of RNA binding." @default.
- W2080071375 created "2016-06-24" @default.
- W2080071375 creator A5002986510 @default.
- W2080071375 creator A5040780127 @default.
- W2080071375 creator A5061896741 @default.
- W2080071375 creator A5063495689 @default.
- W2080071375 creator A5078146498 @default.
- W2080071375 date "2001-06-01" @default.
- W2080071375 modified "2023-10-17" @default.
- W2080071375 title "An Extended RNA Binding Surface through Arrayed S1 and KH Domains in Transcription Factor NusA" @default.
- W2080071375 cites W11564623 @default.
- W2080071375 cites W1502252627 @default.
- W2080071375 cites W1502799086 @default.
- W2080071375 cites W1549766776 @default.
- W2080071375 cites W1549881679 @default.
- W2080071375 cites W1550564033 @default.
- W2080071375 cites W1573998958 @default.
- W2080071375 cites W1582618315 @default.
- W2080071375 cites W1591005472 @default.
- W2080071375 cites W1619155013 @default.
- W2080071375 cites W192412398 @default.
- W2080071375 cites W1942725350 @default.
- W2080071375 cites W1964601737 @default.
- W2080071375 cites W1967506254 @default.
- W2080071375 cites W1973916295 @default.
- W2080071375 cites W1975757622 @default.
- W2080071375 cites W1983115429 @default.
- W2080071375 cites W1986742454 @default.
- W2080071375 cites W1989313294 @default.
- W2080071375 cites W1992358363 @default.
- W2080071375 cites W1995017064 @default.
- W2080071375 cites W2000627319 @default.
- W2080071375 cites W2001550673 @default.
- W2080071375 cites W2001641653 @default.
- W2080071375 cites W2006568501 @default.
- W2080071375 cites W2012839376 @default.
- W2080071375 cites W2014140101 @default.
- W2080071375 cites W2016525744 @default.
- W2080071375 cites W2019812876 @default.
- W2080071375 cites W2019953621 @default.
- W2080071375 cites W2021194721 @default.
- W2080071375 cites W2022058405 @default.
- W2080071375 cites W2026512775 @default.
- W2080071375 cites W2028228325 @default.
- W2080071375 cites W2030949257 @default.
- W2080071375 cites W2032742941 @default.
- W2080071375 cites W2038724843 @default.
- W2080071375 cites W2040195794 @default.
- W2080071375 cites W2041652393 @default.
- W2080071375 cites W2042987185 @default.
- W2080071375 cites W2046488824 @default.
- W2080071375 cites W2054425128 @default.
- W2080071375 cites W2056113159 @default.
- W2080071375 cites W2060945204 @default.
- W2080071375 cites W2066398640 @default.
- W2080071375 cites W2068781790 @default.
- W2080071375 cites W2072973625 @default.
- W2080071375 cites W2074388871 @default.
- W2080071375 cites W2075318985 @default.
- W2080071375 cites W2081643992 @default.
- W2080071375 cites W2082916410 @default.
- W2080071375 cites W2082971321 @default.
- W2080071375 cites W2085655933 @default.
- W2080071375 cites W2092617311 @default.
- W2080071375 cites W2099298539 @default.
- W2080071375 cites W2101402754 @default.
- W2080071375 cites W2107870109 @default.
- W2080071375 cites W2112103350 @default.
- W2080071375 cites W2112275766 @default.
- W2080071375 cites W2112817387 @default.
- W2080071375 cites W2115024759 @default.
- W2080071375 cites W2116844374 @default.
- W2080071375 cites W2119966574 @default.
- W2080071375 cites W2122602899 @default.
- W2080071375 cites W2139033261 @default.
- W2080071375 cites W2142218223 @default.
- W2080071375 cites W2143302607 @default.
- W2080071375 cites W2145358657 @default.
- W2080071375 cites W2150068255 @default.
- W2080071375 cites W2159268439 @default.
- W2080071375 cites W2159491669 @default.
- W2080071375 cites W2170710432 @default.
- W2080071375 cites W218451508 @default.
- W2080071375 cites W2435712174 @default.
- W2080071375 cites W49685849 @default.
- W2080071375 cites W937000772 @default.
- W2080071375 doi "https://doi.org/10.1016/s1097-2765(01)00262-3" @default.
- W2080071375 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/11430821" @default.
- W2080071375 hasPublicationYear "2001" @default.
- W2080071375 type Work @default.
- W2080071375 sameAs 2080071375 @default.
- W2080071375 citedByCount "82" @default.
- W2080071375 countsByYear W20800713752012 @default.
- W2080071375 countsByYear W20800713752013 @default.
- W2080071375 countsByYear W20800713752014 @default.
- W2080071375 countsByYear W20800713752015 @default.
- W2080071375 countsByYear W20800713752016 @default.
- W2080071375 countsByYear W20800713752017 @default.