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- W2080140379 abstract "Fulminant hepatic failure, especially when characterized by deep coma, forebodes severe morbidity and high mortality. The Fulminant Hepatic Failure Surveillance Study reports an overall mortality of 22% in 318 patients, and of those having deep coma only 17.6% survived.1Fulminant hepatitis following halothane anesthesia had the worst prognosis, only 4% of 53 patients surviving. Age above 45 years and the presence of complications also worsened the prognosis. Exchange transfusions offered the best hope for survival, 24% of 166 patients living compared to 10% of 101 patients who received no special treatment. Companion reports by Burnell and by Buckner and their colleagues2,3afford means for comparison of treatment of fulminant hepatic failure by cross circulation or by plasma exchange. Burnell et al applied cross circulation in three patients, one having acute hepatic necrosis of viral origin (presumably serum hepatitis), the second having hepatitis following a second use of halothane" @default.
- W2080140379 created "2016-06-24" @default.
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- W2080140379 date "1973-12-03" @default.
- W2080140379 modified "2023-09-26" @default.
- W2080140379 title "Fulminant Hepatic Failure" @default.
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- W2080140379 doi "https://doi.org/10.1001/jama.1973.03230100049015" @default.
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