FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2080144482> ?p ?o ?g. }

• W2080144482 endingPage "155" @default.
• W2080144482 startingPage "145" @default.
• W2080144482 abstract "Respiratory tract infections may be an important component in many deaths attributed to sudden infant death syndrome (SIDS), although the mechanism of involvement remains unclear.The hypothesis was tested that prolonged hypoxia and a thermogenic state (simulating a fever due to respiratory tract infection) would impair respiratory responsiveness to airway obstruction during sleep.Thirty nine piglets aged 5-7 days were exposed to 24 h of moderate hypoxia and/or a low dose of endotoxin derived from Salmonella abortus equi. Responsiveness to complete and subtotal upper airway obstruction was tested during non-rapid eye movement (NREM) and rapid eye movement (REM) sleep. The end-point for airway obstruction tests was taken as the first protective response, either arousal or initiation of mouth breathing. Responsiveness was assessed as response time and response threshold (measured as respiratory effort, i.e. esophageal pressure swing).All animals demonstrated a thermogenic state following endotoxin delivery (drop in ear temperature of 5.8 +/- 0.2 degrees C and a small but significant increase in rectal temperature). Response time to subtotal airway obstruction was reduced during the heat conserving phase of the fever (thermogenesis; 2.8 +/- 0.5 s compared to 4.3 +/- 0.7 s during pre-endotoxin tests), but markedly increased during the recovery period (20.3 +/- 5.1 compared to 14.0 +/- 2.5 s pre-endotoxin) in NREM sleep. Response threshold was not significantly affected by either endotoxin or hypoxia in NREM sleep. Respiratory responsiveness to subtotal obstruction was markedly reduced during REM sleep (response time 40.3 +/- 10.9 s compared to 14.7 +/- 2.2 s in NREM; response threshold -14.0 +/- 1.3 mm Hg compared to -11.7 +/- 1.0 mm Hg in NREM).This study has demonstrated in a neonatal animal model that respiratory responsiveness to airways obstruction is delayed during recovery from fever. The findings may have implications for the human infant recovering from a respiratory illness." @default.
• W2080144482 created "2016-06-24" @default.
• W2080144482 creator A5022445283 @default.
• W2080144482 creator A5043497497 @default.
• W2080144482 creator A5070077551 @default.
• W2080144482 creator A5078063323 @default.
• W2080144482 date "2005-01-01" @default.
• W2080144482 modified "2023-09-25" @default.
• W2080144482 title "Effects of Prior Hypoxia Exposure, Endotoxin and Sleep State on Arousal Ability to Airway Obstruction in Piglets: Implications for Sudden Infant Death Syndrome" @default.
• W2080144482 cites W1965222718 @default.
• W2080144482 cites W1965446912 @default.
• W2080144482 cites W1977803259 @default.
• W2080144482 cites W1984025123 @default.
• W2080144482 cites W1990006072 @default.
• W2080144482 cites W2000631010 @default.
• W2080144482 cites W2005837824 @default.
• W2080144482 cites W2014898704 @default.
• W2080144482 cites W2015929894 @default.
• W2080144482 cites W2017596698 @default.
• W2080144482 cites W2024552772 @default.
• W2080144482 cites W2025468535 @default.
• W2080144482 cites W2035012119 @default.
• W2080144482 cites W2038016080 @default.
• W2080144482 cites W2045253845 @default.
• W2080144482 cites W2058463290 @default.
• W2080144482 cites W2066544084 @default.
• W2080144482 cites W2082781741 @default.
• W2080144482 cites W2086752982 @default.
• W2080144482 cites W2092572254 @default.
• W2080144482 cites W2098043455 @default.
• W2080144482 cites W2111534945 @default.
• W2080144482 cites W2125075244 @default.
• W2080144482 cites W2128365958 @default.
• W2080144482 cites W2154559128 @default.
• W2080144482 cites W2164250057 @default.
• W2080144482 cites W2166470557 @default.
• W2080144482 cites W2189171835 @default.
• W2080144482 cites W2257418285 @default.
• W2080144482 cites W2287053162 @default.
• W2080144482 cites W2287437468 @default.
• W2080144482 cites W2320750910 @default.
• W2080144482 cites W2335205712 @default.
• W2080144482 cites W2410270370 @default.
• W2080144482 cites W2413011523 @default.
• W2080144482 cites W2418858465 @default.
• W2080144482 cites W4205606874 @default.
• W2080144482 cites W49430721 @default.
• W2080144482 cites W2415628067 @default.
• W2080144482 doi "https://doi.org/10.1159/000085896" @default.
• W2080144482 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/15908744" @default.
• W2080144482 hasPublicationYear "2005" @default.
• W2080144482 type Work @default.
• W2080144482 sameAs 2080144482 @default.
• W2080144482 citedByCount "5" @default.
• W2080144482 countsByYear W20801444822015 @default.
• W2080144482 countsByYear W20801444822022 @default.
• W2080144482 crossrefType "journal-article" @default.
• W2080144482 hasAuthorship W2080144482A5022445283 @default.
• W2080144482 hasAuthorship W2080144482A5043497497 @default.
• W2080144482 hasAuthorship W2080144482A5070077551 @default.
• W2080144482 hasAuthorship W2080144482A5078063323 @default.
• W2080144482 hasConcept C105922876 @default.
• W2080144482 hasConcept C118487528 @default.
• W2080144482 hasConcept C126322002 @default.
• W2080144482 hasConcept C153050134 @default.
• W2080144482 hasConcept C178790620 @default.
• W2080144482 hasConcept C185592680 @default.
• W2080144482 hasConcept C187212893 @default.
• W2080144482 hasConcept C20566671 @default.
• W2080144482 hasConcept C2777935920 @default.
• W2080144482 hasConcept C2778333281 @default.
• W2080144482 hasConcept C2781326671 @default.
• W2080144482 hasConcept C2987955292 @default.
• W2080144482 hasConcept C2993353509 @default.
• W2080144482 hasConcept C42219234 @default.
• W2080144482 hasConcept C540031477 @default.
• W2080144482 hasConcept C71924100 @default.
• W2080144482 hasConcept C7836513 @default.
• W2080144482 hasConcept C99526266 @default.
• W2080144482 hasConceptScore W2080144482C105922876 @default.
• W2080144482 hasConceptScore W2080144482C118487528 @default.
• W2080144482 hasConceptScore W2080144482C126322002 @default.
• W2080144482 hasConceptScore W2080144482C153050134 @default.
• W2080144482 hasConceptScore W2080144482C178790620 @default.
• W2080144482 hasConceptScore W2080144482C185592680 @default.
• W2080144482 hasConceptScore W2080144482C187212893 @default.
• W2080144482 hasConceptScore W2080144482C20566671 @default.
• W2080144482 hasConceptScore W2080144482C2777935920 @default.
• W2080144482 hasConceptScore W2080144482C2778333281 @default.
• W2080144482 hasConceptScore W2080144482C2781326671 @default.
• W2080144482 hasConceptScore W2080144482C2987955292 @default.
• W2080144482 hasConceptScore W2080144482C2993353509 @default.
• W2080144482 hasConceptScore W2080144482C42219234 @default.
• W2080144482 hasConceptScore W2080144482C540031477 @default.
• W2080144482 hasConceptScore W2080144482C71924100 @default.
• W2080144482 hasConceptScore W2080144482C7836513 @default.
• W2080144482 hasConceptScore W2080144482C99526266 @default.
• W2080144482 hasIssue "3" @default.

• next