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- W2080154279 abstract "To determine whether IgG subclass patterns differed between nonpregnant women, healthy pregnant women, and pregnant women with a history of recurrent miscarriage.Controlled clinical study.An academic setting.Group 1 was comprised of 10 nonpregnant women, group 2 of 10 healthy pregnant women, group 3 of eight pregnant women with a history of recurrent miscarriage and whose pregnancies on this occasion went to term, and group 4 of 10 women with a history of recurrent miscarriage whose pregnancies again failed later in the first trimester.None of the patients received any medication.Serum levels of total IgG and IgG 1, 2, 3, and 4.The results obtained showed that normal pregnancy was associated with a significant increase in total IgG production and an increase in IgG subclasses 1, 2, and 3. Women with a history of miscarriage, but who had a successful pregnancy on this occasion, showed a similar pattern of IgG subclasses. Women with a history of miscarriage and whose pregnancy again ended in miscarriage showed a different IgG subclass pattern.Pregnancies that ended in miscarriage showed a different pattern of IgG subclasses than those that continued to term. The changes seen in immunoglobulin patterns could be linked to changes in cytokine production." @default.
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- W2080154279 date "2001-11-01" @default.
- W2080154279 modified "2023-09-28" @default.
- W2080154279 title "Abnormal immunoglobulin subclass patterns in women with a history of recurrent miscarriage" @default.
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- W2080154279 doi "https://doi.org/10.1016/s0015-0282(01)02857-6" @default.
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