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• W2080201104 abstract "Objective. To explore angiogenic factor differences in preeclamptic patients according to the absence or presence of underlying vascular disease.Methods. We prospectively compared serum soluble fms-like tyrosine kinase 1 (sFlt1), soluble endoglin, and placental growth factor (PlGF) from 41 normal-risk and 32 high-risk (preexisting conditions) subjects at serial gestational ages.Results. Median sFlt1 was lower at delivery in preeclamptic patients with underlying chronic hypertension and/or chronic proteinuria (5115 pg/ml) compared with normal risk preeclamptic patients (16375 pg/ml). PlGF was consistently low in patients who developed preeclampsia.Conclusions. Effects of sFlt1 may be contextual, varying according to the health or disease state of vascular endothelium." @default.
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• W2080201104 date "2009-11-09" @default.
• W2080201104 modified "2023-10-14" @default.
• W2080201104 title "Variable expression of soluble fms-like tyrosine kinase 1 in patients at high risk for preeclampsia" @default.
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• W2080201104 doi "https://doi.org/10.3109/14767050903258753" @default.
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