Matches in SemOpenAlex for { <https://semopenalex.org/work/W2080204551> ?p ?o ?g. }
- W2080204551 endingPage "39" @default.
- W2080204551 startingPage "33" @default.
- W2080204551 abstract "Insect flight muscle (IFM) can oscillate at frequencies up to 1000Hz, owing to its capability of stretch activation (SA). It is a highly specialized form of cross striated muscles, and its peculiar features include the IFM-specific isoform of troponin-I (troponin-H or TnH) with an unusually long Pro-Ala-rich extension at the C-terminus. Although we have shown that this extension does not directly take part in SA, questions remain as to what its real role is and why it is expressed only in IFM. Here we explored the structural role of the extension, be comparing X-ray diffraction patterns and electron micrographs of bumblebee IFM fibers before and after enzymatic removal of the extension. The removal had a dramatic effect on diffraction patterns: In IFMs in general, the equatorial 2,0 reflection is much stronger than the 1,1 reflection, but after removal, their intensities became almost equal (stronger 1,1 is a feature of vertebrate skeletal muscle). Electron micrographs revealed that a substantial fraction of the thin filaments showed a tendency to move towards the vertebrate position (the trigonal position between three thick filaments), while the rest of the thin filaments remained in their original insect position (midway between two neighboring thick filaments). Therefore, one of the roles of the extension is suggested to keep the filament lattice in the correct configuration for IFM. This insect-type lattice structure is preserved among IFMs from varied insect orders but not in body muscles, suggesting that the maintenance of this lattice structure is important for flight functions." @default.
- W2080204551 created "2016-06-24" @default.
- W2080204551 creator A5018483373 @default.
- W2080204551 date "2013-07-01" @default.
- W2080204551 modified "2023-09-27" @default.
- W2080204551 title "Flight muscle-specific Pro-Ala-rich extension of troponin is important for maintaining the insect-type myofilament lattice integrity" @default.
- W2080204551 cites W1528266879 @default.
- W2080204551 cites W1906053604 @default.
- W2080204551 cites W1963623972 @default.
- W2080204551 cites W1969947371 @default.
- W2080204551 cites W1972720527 @default.
- W2080204551 cites W1977643106 @default.
- W2080204551 cites W1980588461 @default.
- W2080204551 cites W1981608492 @default.
- W2080204551 cites W1981614598 @default.
- W2080204551 cites W1987052179 @default.
- W2080204551 cites W1990057249 @default.
- W2080204551 cites W2002065158 @default.
- W2080204551 cites W2004862840 @default.
- W2080204551 cites W2007936803 @default.
- W2080204551 cites W2012792837 @default.
- W2080204551 cites W2022656483 @default.
- W2080204551 cites W2030552914 @default.
- W2080204551 cites W2041752769 @default.
- W2080204551 cites W2044931264 @default.
- W2080204551 cites W2052083101 @default.
- W2080204551 cites W2075513362 @default.
- W2080204551 cites W2086026218 @default.
- W2080204551 cites W2103776761 @default.
- W2080204551 cites W2122033424 @default.
- W2080204551 cites W2127138188 @default.
- W2080204551 cites W2132435017 @default.
- W2080204551 cites W2139279770 @default.
- W2080204551 cites W2158645640 @default.
- W2080204551 cites W2163920009 @default.
- W2080204551 cites W2168158185 @default.
- W2080204551 cites W2321839038 @default.
- W2080204551 cites W2513001231 @default.
- W2080204551 cites W62031580 @default.
- W2080204551 doi "https://doi.org/10.1016/j.jsb.2013.05.009" @default.
- W2080204551 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/23707700" @default.
- W2080204551 hasPublicationYear "2013" @default.
- W2080204551 type Work @default.
- W2080204551 sameAs 2080204551 @default.
- W2080204551 citedByCount "4" @default.
- W2080204551 countsByYear W20802045512015 @default.
- W2080204551 countsByYear W20802045512016 @default.
- W2080204551 countsByYear W20802045512017 @default.
- W2080204551 crossrefType "journal-article" @default.
- W2080204551 hasAuthorship W2080204551A5018483373 @default.
- W2080204551 hasConcept C105702510 @default.
- W2080204551 hasConcept C120665830 @default.
- W2080204551 hasConcept C121332964 @default.
- W2080204551 hasConcept C12554922 @default.
- W2080204551 hasConcept C125705527 @default.
- W2080204551 hasConcept C174054327 @default.
- W2080204551 hasConcept C185592680 @default.
- W2080204551 hasConcept C2777314717 @default.
- W2080204551 hasConcept C3018767501 @default.
- W2080204551 hasConcept C55493867 @default.
- W2080204551 hasConcept C6997183 @default.
- W2080204551 hasConcept C7301908 @default.
- W2080204551 hasConcept C8010536 @default.
- W2080204551 hasConcept C86803240 @default.
- W2080204551 hasConcept C93877712 @default.
- W2080204551 hasConcept C97257150 @default.
- W2080204551 hasConcept C97355855 @default.
- W2080204551 hasConceptScore W2080204551C105702510 @default.
- W2080204551 hasConceptScore W2080204551C120665830 @default.
- W2080204551 hasConceptScore W2080204551C121332964 @default.
- W2080204551 hasConceptScore W2080204551C12554922 @default.
- W2080204551 hasConceptScore W2080204551C125705527 @default.
- W2080204551 hasConceptScore W2080204551C174054327 @default.
- W2080204551 hasConceptScore W2080204551C185592680 @default.
- W2080204551 hasConceptScore W2080204551C2777314717 @default.
- W2080204551 hasConceptScore W2080204551C3018767501 @default.
- W2080204551 hasConceptScore W2080204551C55493867 @default.
- W2080204551 hasConceptScore W2080204551C6997183 @default.
- W2080204551 hasConceptScore W2080204551C7301908 @default.
- W2080204551 hasConceptScore W2080204551C8010536 @default.
- W2080204551 hasConceptScore W2080204551C86803240 @default.
- W2080204551 hasConceptScore W2080204551C93877712 @default.
- W2080204551 hasConceptScore W2080204551C97257150 @default.
- W2080204551 hasConceptScore W2080204551C97355855 @default.
- W2080204551 hasIssue "1" @default.
- W2080204551 hasLocation W20802045511 @default.
- W2080204551 hasLocation W20802045512 @default.
- W2080204551 hasOpenAccess W2080204551 @default.
- W2080204551 hasPrimaryLocation W20802045511 @default.
- W2080204551 hasRelatedWork W1629156096 @default.
- W2080204551 hasRelatedWork W1965897429 @default.
- W2080204551 hasRelatedWork W1972896858 @default.
- W2080204551 hasRelatedWork W1989314654 @default.
- W2080204551 hasRelatedWork W2014664809 @default.
- W2080204551 hasRelatedWork W2024549821 @default.
- W2080204551 hasRelatedWork W2122581177 @default.
- W2080204551 hasRelatedWork W2181907140 @default.
- W2080204551 hasRelatedWork W2415403487 @default.