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• W2080207086 abstract "Catch me if you can! Die ClpP-Protease ist ein integraler Bestandteil der Protein-Homöostase und kann effizient durch β-Lactone gehemmt werden. Eine Kombination aus molekularem Modelling, Mutagenese und Kinetikstudien enthüllt jetzt den Mechanismus der ClpP-Inhibition: Eine hydrophobe Tasche neben dem aktiven Zentrum ermöglicht die Bindung von aliphatischen und aromatischen Resten. Das bevorzugte Stereoisomer adressiert das Oxyanion-Loch." @default.
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• W2080207086 date "2013-01-30" @default.
• W2080207086 modified "2023-10-12" @default.
• W2080207086 title "Der Inhibitionsmechanismus der caseinolytischen Protease (ClpP)" @default.
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• W2080207086 doi "https://doi.org/10.1002/ange.201204690" @default.
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