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• W2080211174 abstract "Stroke and peripheral neuropathy are recognized neurological complications of diabetes. Increasing epidemiological evidence also implicates the prediabetic state of impaired glucose tolerance (IGT) as a risk factor for cerebrovascular events and peripheral neuropathy. Data linking IGT to cognitive decline or deficits, however, are less robust. IGT is one component of metabolic syndrome, together with central obesity, hypertension, hypertriglyceridemia and reduced HDL. Each component of metabolic syndrome is an independent risk factor for stroke, but hyperglycemia might be more important than other components in the pathogenesis of neuropathy. Goal-driven diet and exercise regimens, together with pharmacological treatment of hyperlipidemia and hypertension, reduce stroke risk, but the effect of these interventions on neuropathy has not been fully explored." @default.
• W2080211174 created "2016-06-24" @default.
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• W2080211174 date "2006-05-01" @default.
• W2080211174 modified "2023-10-07" @default.
• W2080211174 title "Therapy Insight: neurological complications of prediabetes" @default.
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• W2080211174 doi "https://doi.org/10.1038/ncpneuro0172" @default.
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