FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2080212292> ?p ?o ?g. }

• W2080212292 endingPage "656" @default.
• W2080212292 startingPage "651" @default.
• W2080212292 abstract "Study objective We undertook the present study to investigate the perception of dyspnea (with respect to changes in end-inspiratory and end-expiratory lung volumes), during four different levels of high-intensity constant work rate exercise (CWRE) in patients with severe COPD Design Crossover descriptive study with consecutively recruited subjects Setting Tertiary university hospital Patients Twenty-seven subjects with severe COPD (mean [± SD] age, 65 ± 5 years of age; mean FEV1, 43 ± 8% predicted; and mean inspiratory capacity [IC]; 74 ± 14% predicted) Measurements and results Subjects randomly performed four high-intensity CWRE tests (conducted at 65%, 75%, 85%, and 95% of their symptom-limited peak work rate). Dyspnea, leg fatigue, and IC were determined every 2 min during exercise with breath-by-breath gas exchange and ventilatory measurements. There was a good correlation between the resting IC percent predicted and the oxygen uptake ( V . o2) peak (r= 0.64 to 0.69 between the IC percent predicted and V . o2peak at the four work rates). There were significant differences (p < 0.01) in mean respiratory rate (33 ± 6, 35 ± 6, 37 ± 6, and 38 ± 6 min), peak dyspnea score (5.9 ± 1.3, 6.3 ± 1.4, 6.8 ± 1.2, and 6.9 ± 1.6), minute ventilation (45.0 ± 8.7, 43.8 ± 7.7, 43.1 ± 8.7, and 42.8 ± 8.0 L/min), leg fatigue (4.8 ± 1.3, 5.1 ± 1.3, 5.7 ± 1.4, and 5.8 ± 1.4), and end-tidal carbon dioxide partial pressure (4.41 ± 0.36, 4.53 ± 0.33, 4.66 ± 0.31, and 4.76 ± 0.24 kPa), respectively, for tests conducted at 65%, 75%, 85%, and 95% of their symptom-limited peak work rate, and in mean end-expiratory lung volume ([EELV] 4.55 ± 0.44, 4.69 ± 0.43, and 4.79 ± 0.43 L), respectively, for tests conducted at 65%, 75%, and 85% of their symptom-limited peak work rate. In multivariable analysis, the factors that were independently correlated with dyspnea (p < 0.05) were EELV, peak inspiratory flow, and leg fatigue/discomfort Conclusion In COPD subjects with flow limitation at rest, the perception of dyspnea increased nonlinearly with the magnitude of high-intensity CWRE in association with a faster respiratory pattern and an increase in EELV. At the highest work rates, it appeared that a reduction in tidal volume and ventilation peak may have limited the tolerance to exercise We undertook the present study to investigate the perception of dyspnea (with respect to changes in end-inspiratory and end-expiratory lung volumes), during four different levels of high-intensity constant work rate exercise (CWRE) in patients with severe COPD Crossover descriptive study with consecutively recruited subjects Tertiary university hospital Twenty-seven subjects with severe COPD (mean [± SD] age, 65 ± 5 years of age; mean FEV1, 43 ± 8% predicted; and mean inspiratory capacity [IC]; 74 ± 14% predicted) Subjects randomly performed four high-intensity CWRE tests (conducted at 65%, 75%, 85%, and 95% of their symptom-limited peak work rate). Dyspnea, leg fatigue, and IC were determined every 2 min during exercise with breath-by-breath gas exchange and ventilatory measurements. There was a good correlation between the resting IC percent predicted and the oxygen uptake ( V . o2) peak (r= 0.64 to 0.69 between the IC percent predicted and V . o2peak at the four work rates). There were significant differences (p < 0.01) in mean respiratory rate (33 ± 6, 35 ± 6, 37 ± 6, and 38 ± 6 min), peak dyspnea score (5.9 ± 1.3, 6.3 ± 1.4, 6.8 ± 1.2, and 6.9 ± 1.6), minute ventilation (45.0 ± 8.7, 43.8 ± 7.7, 43.1 ± 8.7, and 42.8 ± 8.0 L/min), leg fatigue (4.8 ± 1.3, 5.1 ± 1.3, 5.7 ± 1.4, and 5.8 ± 1.4), and end-tidal carbon dioxide partial pressure (4.41 ± 0.36, 4.53 ± 0.33, 4.66 ± 0.31, and 4.76 ± 0.24 kPa), respectively, for tests conducted at 65%, 75%, 85%, and 95% of their symptom-limited peak work rate, and in mean end-expiratory lung volume ([EELV] 4.55 ± 0.44, 4.69 ± 0.43, and 4.79 ± 0.43 L), respectively, for tests conducted at 65%, 75%, and 85% of their symptom-limited peak work rate. In multivariable analysis, the factors that were independently correlated with dyspnea (p < 0.05) were EELV, peak inspiratory flow, and leg fatigue/discomfort In COPD subjects with flow limitation at rest, the perception of dyspnea increased nonlinearly with the magnitude of high-intensity CWRE in association with a faster respiratory pattern and an increase in EELV. At the highest work rates, it appeared that a reduction in tidal volume and ventilation peak may have limited the tolerance to exercise" @default.
• W2080212292 created "2016-06-24" @default.
• W2080212292 creator A5009244190 @default.
• W2080212292 creator A5017343454 @default.
• W2080212292 creator A5019572229 @default.
• W2080212292 creator A5065005982 @default.
• W2080212292 creator A5076485405 @default.
• W2080212292 creator A5082653234 @default.
• W2080212292 date "2005-08-01" @default.
• W2080212292 modified "2023-10-17" @default.
• W2080212292 title "Dyspnea, Ventilatory Pattern, and Changes in Dynamic Hyperinflation Related to the Intensity of Constant Work Rate Exercise in COPD" @default.
• W2080212292 cites W1529195928 @default.
• W2080212292 cites W1976119118 @default.
• W2080212292 cites W1978421244 @default.
• W2080212292 cites W1982542411 @default.
• W2080212292 cites W2001097201 @default.
• W2080212292 cites W2004008756 @default.
• W2080212292 cites W2023170336 @default.
• W2080212292 cites W2034714226 @default.
• W2080212292 cites W2082466126 @default.
• W2080212292 cites W2083926687 @default.
• W2080212292 cites W2087551281 @default.
• W2080212292 cites W2114479159 @default.
• W2080212292 cites W2117250400 @default.
• W2080212292 cites W2127159607 @default.
• W2080212292 cites W2144279695 @default.
• W2080212292 cites W2144451402 @default.
• W2080212292 cites W2152906506 @default.
• W2080212292 cites W2176052317 @default.
• W2080212292 cites W2262523178 @default.
• W2080212292 cites W2327738006 @default.
• W2080212292 cites W2443232192 @default.
• W2080212292 cites W2604596332 @default.
• W2080212292 cites W4233968038 @default.
• W2080212292 cites W59993760 @default.
• W2080212292 cites W786985012 @default.
• W2080212292 doi "https://doi.org/10.1378/chest.128.2.651" @default.
• W2080212292 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/16100150" @default.
• W2080212292 hasPublicationYear "2005" @default.
• W2080212292 type Work @default.
• W2080212292 sameAs 2080212292 @default.
• W2080212292 citedByCount "76" @default.
• W2080212292 countsByYear W20802122922012 @default.
• W2080212292 countsByYear W20802122922013 @default.
• W2080212292 countsByYear W20802122922014 @default.
• W2080212292 countsByYear W20802122922015 @default.
• W2080212292 countsByYear W20802122922016 @default.
• W2080212292 countsByYear W20802122922017 @default.
• W2080212292 countsByYear W20802122922018 @default.
• W2080212292 countsByYear W20802122922019 @default.
• W2080212292 countsByYear W20802122922020 @default.
• W2080212292 countsByYear W20802122922021 @default.
• W2080212292 countsByYear W20802122922022 @default.
• W2080212292 countsByYear W20802122922023 @default.
• W2080212292 crossrefType "journal-article" @default.
• W2080212292 hasAuthorship W2080212292A5009244190 @default.
• W2080212292 hasAuthorship W2080212292A5017343454 @default.
• W2080212292 hasAuthorship W2080212292A5019572229 @default.
• W2080212292 hasAuthorship W2080212292A5065005982 @default.
• W2080212292 hasAuthorship W2080212292A5076485405 @default.
• W2080212292 hasAuthorship W2080212292A5082653234 @default.
• W2080212292 hasConcept C121332964 @default.
• W2080212292 hasConcept C126322002 @default.
• W2080212292 hasConcept C127413603 @default.
• W2080212292 hasConcept C164705383 @default.
• W2080212292 hasConcept C1862650 @default.
• W2080212292 hasConcept C200457457 @default.
• W2080212292 hasConcept C27101514 @default.
• W2080212292 hasConcept C2776780178 @default.
• W2080212292 hasConcept C2776924770 @default.
• W2080212292 hasConcept C2777257755 @default.
• W2080212292 hasConcept C2777714996 @default.
• W2080212292 hasConcept C2777953023 @default.
• W2080212292 hasConcept C2779975672 @default.
• W2080212292 hasConcept C2781094410 @default.
• W2080212292 hasConcept C42219234 @default.
• W2080212292 hasConcept C534529494 @default.
• W2080212292 hasConcept C62520636 @default.
• W2080212292 hasConcept C71924100 @default.
• W2080212292 hasConcept C78519656 @default.
• W2080212292 hasConcept C8213797 @default.
• W2080212292 hasConcept C84393581 @default.
• W2080212292 hasConcept C93038891 @default.
• W2080212292 hasConceptScore W2080212292C121332964 @default.
• W2080212292 hasConceptScore W2080212292C126322002 @default.
• W2080212292 hasConceptScore W2080212292C127413603 @default.
• W2080212292 hasConceptScore W2080212292C164705383 @default.
• W2080212292 hasConceptScore W2080212292C1862650 @default.
• W2080212292 hasConceptScore W2080212292C200457457 @default.
• W2080212292 hasConceptScore W2080212292C27101514 @default.
• W2080212292 hasConceptScore W2080212292C2776780178 @default.
• W2080212292 hasConceptScore W2080212292C2776924770 @default.
• W2080212292 hasConceptScore W2080212292C2777257755 @default.
• W2080212292 hasConceptScore W2080212292C2777714996 @default.
• W2080212292 hasConceptScore W2080212292C2777953023 @default.
• W2080212292 hasConceptScore W2080212292C2779975672 @default.
• W2080212292 hasConceptScore W2080212292C2781094410 @default.
• W2080212292 hasConceptScore W2080212292C42219234 @default.

• next