FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2080222318> ?p ?o ?g. }

• W2080222318 endingPage "587" @default.
• W2080222318 startingPage "581" @default.
• W2080222318 abstract "Little is known about the architecture and biochemical composition of the eukaryotic DNA replication fork. To study this problem, we used biotin-streptavidin-modified plasmids to induce sequence-specific replication fork pausing in Xenopus egg extracts. Chromatin immunoprecipitation was employed to identify factors associated with the paused fork. This approach identifies DNA pol alpha, DNA pol delta, DNA pol epsilon, MCM2-7, Cdc45, GINS, and Mcm10 as components of the vertebrate replisome. In the presence of the DNA polymerase inhibitor aphidicolin, which causes uncoupling of a highly processive DNA helicase from the stalled replisome, only Cdc45, GINS, and MCM2-7 are enriched at the pause site. The data suggest the existence of a large molecular machine, the unwindosome, which separates DNA strands at the replication fork and contains Cdc45, GINS, and the MCM2-7 holocomplex." @default.
• W2080222318 created "2016-06-24" @default.
• W2080222318 creator A5054590528 @default.
• W2080222318 creator A5057536779 @default.
• W2080222318 creator A5060388622 @default.
• W2080222318 creator A5077987097 @default.
• W2080222318 creator A5080203458 @default.
• W2080222318 date "2006-02-01" @default.
• W2080222318 modified "2023-10-17" @default.
• W2080222318 title "Localization of MCM2-7, Cdc45, and GINS to the Site of DNA Unwinding during Eukaryotic DNA Replication" @default.
• W2080222318 cites W1964439976 @default.
• W2080222318 cites W1968074226 @default.
• W2080222318 cites W1974394081 @default.
• W2080222318 cites W1985710832 @default.
• W2080222318 cites W1986773553 @default.
• W2080222318 cites W1998415606 @default.
• W2080222318 cites W2003279154 @default.
• W2080222318 cites W2013321725 @default.
• W2080222318 cites W2016193895 @default.
• W2080222318 cites W2023282529 @default.
• W2080222318 cites W2023292223 @default.
• W2080222318 cites W2038692966 @default.
• W2080222318 cites W2041903626 @default.
• W2080222318 cites W2047998400 @default.
• W2080222318 cites W2056590571 @default.
• W2080222318 cites W2057896961 @default.
• W2080222318 cites W2070127489 @default.
• W2080222318 cites W2076101453 @default.
• W2080222318 cites W2082507962 @default.
• W2080222318 cites W2085898164 @default.
• W2080222318 cites W2088658210 @default.
• W2080222318 cites W2089942288 @default.
• W2080222318 cites W2092296056 @default.
• W2080222318 cites W2108654668 @default.
• W2080222318 cites W2109962174 @default.
• W2080222318 cites W2113194068 @default.
• W2080222318 cites W2122808742 @default.
• W2080222318 cites W2123878119 @default.
• W2080222318 cites W2126918645 @default.
• W2080222318 cites W2134156532 @default.
• W2080222318 cites W2150000259 @default.
• W2080222318 cites W2169154042 @default.
• W2080222318 cites W2170609809 @default.
• W2080222318 cites W2083389050 @default.
• W2080222318 doi "https://doi.org/10.1016/j.molcel.2006.01.030" @default.
• W2080222318 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/16483939" @default.
• W2080222318 hasPublicationYear "2006" @default.
• W2080222318 type Work @default.
• W2080222318 sameAs 2080222318 @default.
• W2080222318 citedByCount "329" @default.
• W2080222318 countsByYear W20802223182012 @default.
• W2080222318 countsByYear W20802223182013 @default.
• W2080222318 countsByYear W20802223182014 @default.
• W2080222318 countsByYear W20802223182015 @default.
• W2080222318 countsByYear W20802223182016 @default.
• W2080222318 countsByYear W20802223182017 @default.
• W2080222318 countsByYear W20802223182018 @default.
• W2080222318 countsByYear W20802223182019 @default.
• W2080222318 countsByYear W20802223182020 @default.
• W2080222318 countsByYear W20802223182021 @default.
• W2080222318 countsByYear W20802223182022 @default.
• W2080222318 countsByYear W20802223182023 @default.
• W2080222318 crossrefType "journal-article" @default.
• W2080222318 hasAuthorship W2080222318A5054590528 @default.
• W2080222318 hasAuthorship W2080222318A5057536779 @default.
• W2080222318 hasAuthorship W2080222318A5060388622 @default.
• W2080222318 hasAuthorship W2080222318A5077987097 @default.
• W2080222318 hasAuthorship W2080222318A5080203458 @default.
• W2080222318 hasBestOaLocation W20802223181 @default.
• W2080222318 hasConcept C104317684 @default.
• W2080222318 hasConcept C104690221 @default.
• W2080222318 hasConcept C149187182 @default.
• W2080222318 hasConcept C151158763 @default.
• W2080222318 hasConcept C153911025 @default.
• W2080222318 hasConcept C156719811 @default.
• W2080222318 hasConcept C161223559 @default.
• W2080222318 hasConcept C175248279 @default.
• W2080222318 hasConcept C188036394 @default.
• W2080222318 hasConcept C2756471 @default.
• W2080222318 hasConcept C54355233 @default.
• W2080222318 hasConcept C552990157 @default.
• W2080222318 hasConcept C66072924 @default.
• W2080222318 hasConcept C67705224 @default.
• W2080222318 hasConcept C73573662 @default.
• W2080222318 hasConcept C86803240 @default.
• W2080222318 hasConcept C88354546 @default.
• W2080222318 hasConcept C95444343 @default.
• W2080222318 hasConcept C98086919 @default.
• W2080222318 hasConceptScore W2080222318C104317684 @default.
• W2080222318 hasConceptScore W2080222318C104690221 @default.
• W2080222318 hasConceptScore W2080222318C149187182 @default.
• W2080222318 hasConceptScore W2080222318C151158763 @default.
• W2080222318 hasConceptScore W2080222318C153911025 @default.
• W2080222318 hasConceptScore W2080222318C156719811 @default.
• W2080222318 hasConceptScore W2080222318C161223559 @default.
• W2080222318 hasConceptScore W2080222318C175248279 @default.
• W2080222318 hasConceptScore W2080222318C188036394 @default.
• W2080222318 hasConceptScore W2080222318C2756471 @default.

• next