FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2080223857> ?p ?o ?g. }

• W2080223857 endingPage "159" @default.
• W2080223857 startingPage "139" @default.
• W2080223857 abstract "Abstract The source specificity and biosynthesis of cyclic isoprenoids such as hopanoids, sterols and pentacyclic triterpenoids, which are commonly used as biomarkers in organic geochemistry, is reviewed. Advances in molecular biology have provided much new information about the identity of isoprenoid lipid synthesis genes, which now makes it possible to confirm whether the biosynthetic capability to produce a particular biomarker exists in an organism or not. Such information will allow organic geochemists to use biomarkers to assign sources of organic matter with more confidence and opens up the possibility of using fossil rDNA in younger sediments as the ultimate biomarker. In ancient sediments the presence of a biomarker may only provide information about the existence of a biosynthetic pathway rather than the presence of a particular group of organisms. For such applications, it is vital that we understand how biochemical pathways have evolved over time, in parallel with the well-recognised evolution of species on earth as codified in the three kingdoms of life – Archaea, Bacteria and Eukaryota. It has become clear that the cyclases that produce hopanoids from squalene (so-called SHCs) and sterols and pentacyclic triterpenoids from oxidosqualene (OSCs) are closely related and reflect evolutionary changes in this biosynthetic pathway over time. There has been much debate whether the sterols that have been detected in some cyanobacterial cultures are produced by de novo synthesis, and there is growing evidence that they might be derived from contaminating organisms such as yeasts and fungi or in some cases result from laboratory contamination or sterols in the culture medium. The presence of 4-methylsterols in some bacteria shows that some of the necessary biochemical apparatus is present in a few prokaryotes. The genomes of several cyanobacteria have been fully sequenced and amongst the genes recognized are several that have a close sequence match to genes related to sterol biosynthesis. These include a putative Δ 24 sterol C-methyltransferase gene, another coding a sterol C-methyltransferase and another for a sterol C-5-desaturase (or C-4 methyl sterol oxidase), but this is only a part of the full complement of genes needed for sterol biosynthesis." @default.
• W2080223857 created "2016-06-24" @default.
• W2080223857 creator A5078340275 @default.
• W2080223857 date "2005-02-01" @default.
• W2080223857 modified "2023-10-12" @default.
• W2080223857 title "Sterols and other triterpenoids: source specificity and evolution of biosynthetic pathways" @default.
• W2080223857 cites W139715951 @default.
• W2080223857 cites W1484626650 @default.
• W2080223857 cites W1498691846 @default.
• W2080223857 cites W1500902190 @default.
• W2080223857 cites W1510467857 @default.
• W2080223857 cites W1513289534 @default.
• W2080223857 cites W1574491302 @default.
• W2080223857 cites W1600443923 @default.
• W2080223857 cites W1602534227 @default.
• W2080223857 cites W1607659620 @default.
• W2080223857 cites W1812872344 @default.
• W2080223857 cites W1869259190 @default.
• W2080223857 cites W1881446470 @default.
• W2080223857 cites W1912527875 @default.
• W2080223857 cites W1929126126 @default.
• W2080223857 cites W1934856134 @default.
• W2080223857 cites W1964044437 @default.
• W2080223857 cites W1967214983 @default.
• W2080223857 cites W1971155442 @default.
• W2080223857 cites W1971292778 @default.
• W2080223857 cites W1972392332 @default.
• W2080223857 cites W1974460286 @default.
• W2080223857 cites W1974833847 @default.
• W2080223857 cites W1976540634 @default.
• W2080223857 cites W1980677539 @default.
• W2080223857 cites W1982024019 @default.
• W2080223857 cites W1987127683 @default.
• W2080223857 cites W1987662358 @default.
• W2080223857 cites W1993281379 @default.
• W2080223857 cites W1993558309 @default.
• W2080223857 cites W1994303129 @default.
• W2080223857 cites W1996173391 @default.
• W2080223857 cites W1996345812 @default.
• W2080223857 cites W1997824577 @default.
• W2080223857 cites W1998353885 @default.
• W2080223857 cites W2000468537 @default.
• W2080223857 cites W2000987452 @default.
• W2080223857 cites W2001213451 @default.
• W2080223857 cites W2002470296 @default.
• W2080223857 cites W2004877121 @default.
• W2080223857 cites W2004905580 @default.
• W2080223857 cites W2008033809 @default.
• W2080223857 cites W2008559554 @default.
• W2080223857 cites W2009892269 @default.
• W2080223857 cites W2011029541 @default.
• W2080223857 cites W2012257797 @default.
• W2080223857 cites W2012290406 @default.
• W2080223857 cites W2012486473 @default.
• W2080223857 cites W2017320488 @default.
• W2080223857 cites W2017867653 @default.
• W2080223857 cites W2019676734 @default.
• W2080223857 cites W2025185153 @default.
• W2080223857 cites W2029701406 @default.
• W2080223857 cites W2030310672 @default.
• W2080223857 cites W2031996103 @default.
• W2080223857 cites W2032247127 @default.
• W2080223857 cites W2036533831 @default.
• W2080223857 cites W2036815970 @default.
• W2080223857 cites W2037084529 @default.
• W2080223857 cites W2037433993 @default.
• W2080223857 cites W2040113174 @default.
• W2080223857 cites W2041462919 @default.
• W2080223857 cites W2044422186 @default.
• W2080223857 cites W2044466382 @default.
• W2080223857 cites W2046055819 @default.
• W2080223857 cites W2046870543 @default.
• W2080223857 cites W2048273599 @default.
• W2080223857 cites W2049770318 @default.
• W2080223857 cites W2049842447 @default.
• W2080223857 cites W2050293242 @default.
• W2080223857 cites W2051257038 @default.
• W2080223857 cites W2052794190 @default.
• W2080223857 cites W2053041342 @default.
• W2080223857 cites W2053640801 @default.
• W2080223857 cites W2054671683 @default.
• W2080223857 cites W2057462478 @default.
• W2080223857 cites W2057907380 @default.
• W2080223857 cites W2059831950 @default.
• W2080223857 cites W2064070855 @default.
• W2080223857 cites W2065235605 @default.
• W2080223857 cites W2066043762 @default.
• W2080223857 cites W2066061120 @default.
• W2080223857 cites W2066980677 @default.
• W2080223857 cites W2067099347 @default.
• W2080223857 cites W2067691579 @default.
• W2080223857 cites W2068991842 @default.
• W2080223857 cites W2069337858 @default.
• W2080223857 cites W2069629978 @default.
• W2080223857 cites W2069932011 @default.
• W2080223857 cites W2070470282 @default.
• W2080223857 cites W2070475831 @default.
• W2080223857 cites W2071983027 @default.

• next