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• W2080227247 abstract "A commercial aqueous stem bark extract of Mangifera indica L. (Vimang) has been reported to have antiinflammatory, immunomodulatory and antioxidant activities. The molecular basis for these diverse properties is still unknown. This study shows that a stem bark extract of M. indica inhibits early and late events in T cell activation, including CD25 cell surface expression, progression to the S-phase of the cell cycle and proliferation in response to T cell receptor (TCR) stimulation. Moreover, the extract prevented TNFalpha-induced IkappaBalpha degradation and the binding of NF-kappaB to the DNA. This study may help to explain at the molecular level some of the biological activities attributed to the aqueous stem bark extract of M. indica (Vimang)." @default.
• W2080227247 created "2016-06-24" @default.
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• W2080227247 date "2005-01-01" @default.
• W2080227247 modified "2023-10-14" @default.
• W2080227247 title "An aqueous stem bark extract ofMangifera indica (Vimang®) inhibits T cell proliferation and TNF-induced activation of nuclear transcription factor NF-κB" @default.
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• W2080227247 doi "https://doi.org/10.1002/ptr.1656" @default.
• W2080227247 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/15934029" @default.
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